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When “The Blob” Made It Hotter Under the Water
… impact on marine microbial communities. The Science A team of researchers tracked the impact of a large-scale heatwave event in the ocean known as “The … Science Program . The proposal focuses on uncovering the metabolic networks involved in carbon and nutrient flux in …
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Dan Rokhsar
… directed towards the sequencing, annotation, and analysis of three human chromosomes. After successful completion of the Human Genome Project, Professor Dr. Rokhsar ’s team has continued to develop … Publications … Selected Publications …
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Evolution of a Fungal Gene Expression Regulator
… Describing the largest analysis to date of the modified DNA base 5mC variations in fungi. The … themselves can also be modified. The best-known example of a modified DNA base is a methylation of the base cytosine … between genome-wide 5mC abundance and the abundance of specific 5mC methyltransferase (MTase) variants. Using new …
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User Advisory Committees
… All staff members of the US Department of Energy (DOE) Joint Genome Institute (JGI) commit to … on JGI Advisory Committees are outlined in this Code of Conduct. … users and their science including technical capabilities offered, proposal review procedures and the annual meeting. …
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Better Genome Editing for Bioenergy
… A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in … tool will make the right cut, researchers created a set of guide RNAs that were effective against 94 percent of the … four sharpening the axe.” In this study,  published in  Metabolic Engineering , a team of researchers likewise honed …
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DAS Tool for Genome Reconstruction from Metagenomes
… been utilizing metagenomics as a way to study a collection of hard-to-culture microbes, but the efficacy of this approach would be greatly increased by having the … of community members and their genome-encoded metabolic capabilities and interactions. Supported by JGI’s …
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In Hot Spring Microbial Mat, Viruses Ride “Piggyback”
… a microbial mat. The Science In microbial mats, communities of microorganisms live among viruses that infect them. But … interactions? Do generalist viruses run rampant, capable of infecting different host species? Or, do they tend to … turnover of microbial prey, and thus able to influence the metabolic rate of microbial communities. Because microbial …
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Genome sequence of Phaeobacter inhibens type strain (T5T), a secondary metabolite producing representative of the marine Roseobacter clade, and emendation of the species description of Phaeobacter inhibens
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You Can Move, But You Can’t Hide
… to replicate themselves and spread from cell to cell. Two of the most common forms of MGEs are viruses and plasmids. They can be found in … now, most other tools have focused on identifying only specific plasmids or viruses. geNomad combines a broad … The U.S. Department of Energy Joint Genome Institute …
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Identifying the Microbial Cleanup Crew at a Superfund Site
… PCE (perchloroethylene) found its way into the groundwater of several communities in New Mexico via leakage from a … bioremediate toxic substances has led to the development of cost-effective environmental cleanup strategies. Summary … growth. In this instance, vegetable oil was injected into a specific type of food that was in the contaminated aquifer …
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Sequencing Sphagnum Leads to Discovery of Sex Chromosomes
… A nuanced understanding of peat moss drives insight into carbon storage   The … By sequencing the genome, researchers were able to pinpoint specific U/V chromosomes (‘U’ for female and ‘V’ for male) … sex chromosomes ever identified in the plant kingdom. Specifically, researchers found that female plants within a …
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A Natural Mechanism Can Turbocharge Viral Evolution
… Understanding how a fundamental mechanism of evolution allows microbes to adapt to changing … means using proteins on its tail fibers to latch onto a specific target on the microbial cell’s membrane. Two decades ago, a team discovered a group of viruses that had in their genomes a surprising tool: a …
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