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… Meta-omics datasets show that CRISPR-Cas systems determine mutualism or parasitism between some archaeal hosts and their hitchhikers. The Science Within the archaeal domain, there is a group of tiny … onto a larger host — often, a fellow archaeal microbe. Understanding how these hosts and hitchhikers coexist is key …

… Retracing how the dry rot Serpula lacrymans adapted to a new … rot fungi reveals the genomic changes Serpula lacrymans has undergone in adapting to manmade environments. The Impact … to see how the Serpula fungi have adapted in an environment with little to no competitors for resources. On wood blocks …

… on microbial communities than ever before — especially with the prospect of meta-analyses boosted by AI and Machine … stable, heavy isotopes, SIP allows researchers to go beyond understanding which microbes are present in a sample, to … In the last year, JGI’s user community has helped propel multiple efforts along these lines, all with the goals of …

… Dr. Visel joined the DOE Joint Genome Institute in 2010. As the Deputy for Science … Axel Visel is the JGI's Deputy for Science Programs. Click to learn more about our seven science program — their areas of focus, major initiatives and more.  … of scientific policy, engaging in interactions with the scientific community at large. …

… Machine learning methods were applied on sequenced fungal genomes to … the largest class of fungi, by lifestyles. The machine “learned” to identify data generated in part through … a DOE Office of Science User Facility, is supported under Contract No. DE-AC02-05CH11231. The work was also …

… Newly developed chemiluminescent biosensors shed light on how bacteria function and … is found in nearly all types of bacteria and interacts with cell signaling networks that control many basic … including plants, soil, and the gut. To better understand the dynamics of this molecule, researchers …

… In honor of the JGI's 25th anniversary in 2022, we have … National Laboratory – jointly the Nobel Prize in Chemistry with Emmanuelle Charpentier of the Max Planck Institute! … nature was using it to do something important.” Related Publications:  A scoutRNA Is Required for Some Type V …

… An improved genome assembly to support targeted tree breeding for the bioeconomy.   The Science Researchers report a … July edition of the journal G3 Genes | Genomes | Genetics , with significant advances compared to the 2014 Eucalyptus … are already working toward a eucalyptus pangenome to better understand the genetic structural diversity of the genus. …

… Cas14 proteins discovered from JGI’s IMG/M database and biochemically … of California (UC), Berkeley, which is also affiliated with the Innovative Genomics Institute. The Impact The … and complex disease. Finally, gene editing is being used to understand how a person’s genetic makeup predisposes them …

… Trained on environmental data, a new JGI tool more accurately … large language models—artificial intelligence trained to understand, generate and manipulate the human language—are … language of biology — and primed for integration with artificial intelligence tools.  LLMs aren’t just for …

… The Integrative Genomics Building (IGB) seen above is home to the DOE Joint Genome … April 2024 — through serving an increased number of users with a record output of products, making data easier to … processed 13,700 metabolomics samples With our users, 247 publications were published   …

… New genomes highlight the diversity of white rot fungi in the genus Lentinula   The Science Shiitake mushrooms get … sequences, this work expands the family tree for Lentinula. Within those samples, this study also tracks the enzymes … hemicellulose, and the toughest molecule, lignin. Understanding Lentinula genomes and their evolution could …