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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
The Science Within the archaeal domain, there is a group of tiny hitchhikers. These organisms are abundant and yet … convert it to usable organic compounds. However, no microbe works alone. Archaea, bacteria, and viruses all operate in concert to form the …
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When “The Blob” Made It Hotter Under the Water
Data from marine heatwave event may foreshadow climate change impact on … water samples when The Blob started. The samples were taken up and down the water column along the Line P transect, a … . The proposal focuses on uncovering the metabolic networks involved in carbon and nutrient flux in marine …
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Ben Bowen
… in mass spectrometry-centered projects, Dr. Bowen’s work focuses on developing high-performance computing … facilitates impactful scientific discoveries, supporting the DOE’s Biological and Environmental Research … Exometabolite niche partitioning among sympatric soil bacteria. Nature communications, 6(1), 8289. Yao, Y., Sun, …
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FOAM (Functional Ontology Assignments for Metagenomes): a Hidden Markov Model (HMM) database with environmental focus
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JGIota: Looking Back at Methane-Making Microbes
We count on livestock for food and fiber, but raising these animals also produces an atmosphere-warming gas: … Those emissions mainly come from gut microbes — the bacteria and archaea breaking down plant matter. So since 2010, the JGI has supported researchers studying those microbial …
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Applying Viral Genomics Expertise to Understanding the Human Virome
… focused on tool development. Specifically, the goal of this work is to develop tools, curated databases, and streamlined … genomes. This includes (i) classifying viruses into groups that can be compared across studies, (ii) predicting … prediction for metagenome-derived viruses of archaea and bacteria ( PLoS Biol , 2023). These tools have significantly …
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An Automated Tool for Assessing Virus Data Quality
… fragments and data quality. The Science Through advances in sequencing technologies and computational approaches, … for characterizing uncultivated viruses. Following up on those guidelines, JGI researchers have now developed … tool called CheckV that can automatically do both. The work was led by research scientist Stephen Nayfach, the …
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Better Genome Editing for Bioenergy
… part of CRISPR-Cas9 technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a … problem: at a genetic level, how does  Y. lipolytica work? The project was a multi-institutional effort led by … could be used for renewable fuel. In fact, lipids can make up more than 90 percent of the microbe’s dry weight. In …
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Expanding Virophage Diversity
… are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant viruses. Virophages … Kb. Additionally, the gene counts have similarly gone up from 13-25 to 12-39. “Overall,” the team concluded, “we … 2018 Viral EcoGenomics & Applications (VEGA) Symposium. The work also used resources of the National Energy Research …
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Finding the Fermenters
… called fermentation. To better understand the range of bacteria and archaea that rely on this form of metabolism, … Research (BER) program to enable scientific discovery in support of the DOE mission. Fermentative metabolism occurs in … between the predicted and actual end products. … This work was supported by the United States Department of …
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16S rRNA Gene Amplicon Sequencing Data from Flooded Rice Paddy Mesocosms Treated with Different Silicon-Rich Soil Amendments
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JGI@25: A Single Cell, Myriad Microbial Discoveries
In honor of the JGI's 25th anniversary in 2022, we have … first closed and finished genome derived from an uncultured bacterial single cell – a symbiont of the green … In 2017, the first New Lineages of Life (NeLLi) workshop was held, inviting the research community to …
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