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JGI@25: From Life at the Extremes to Editing Genomes
… National Laboratory – jointly the Nobel Prize in Chemistry with Emmanuelle Charpentier of the Max Planck Institute! … This is the first science Nobel awarded to two women, with Charpentier and Doudna bringing the total number of … nature was using it to do something important.” Related Publications:  A scoutRNA Is Required for Some Type V …
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JGI@25: Studying Sorghum’s Survival Skills
… biofuels thanks to its drought and flood hardiness. Even with little water, full sunlight and hot temperatures, … Genome roster. Sorghum has an important feature in common with certain other cereal crops: It performs C4 … reference genome for Sorghum bicolor . Since then, 2,993 publications, 107 patent applications, and 53 patents have …
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Charting Progress toward Professional Goals
… Students can apply for internships and work onsite with an experienced researcher who serves as their mentor. … experiences.  Genomic data scientist Deanna Beatty sat down with interns hosted at the JGI through three different … Jacobs participated in the SEED Scholars @ LBNL program,  with support from  the SEED program at UC Berkeley. Sally …
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An Integrated Dataset to Understand Ecosystem Interaction
… revealed key metabolic pathways and metabolites associated with the tree’s stress response. Finally, using … — illuminating the molecular mechanisms for adaptation within the trees. The data set generated is 25 terabytes in … Laboratory (Berkeley Lab). All of this information — 318 metagenomes, 98 plant transcriptomes and 314 metabolomic …
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You Can Move, But You Can’t Hide
… at Lawrence Berkeley National Laboratory (Berkeley Lab), with computing resources provided by NERSC, another user … Over time, MGEs can help microbes gain a competitive edge within an ecosystem. They influence the composition of the … currently has more than 700,000 plasmids from genomes, metagenomes and metatranscriptomes. To lower barriers to …
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A New Actinobacterial Chapter in the Genomic Encyclopedia of Bacteria and Archaea
… Large-scale comparative analysis leads to identification of … with nearly 5,000 publicly available ones and 1,100 metagenome-assembled genomes (MAGs) reconstructed from … resource, but also yielding and supporting many high-impact publications ,” emphasized Markus Göker, who managed the …
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A Natural Mechanism Can Turbocharge Viral Evolution
… a virus and microbial cell is an embrace. For a virus with a “head-tail” morphology, this means using proteins on … sampled all at once from the same environment, called metagenomes. Why? Simon Roux, who led the research team and … at the JGI, thinks that if you’re a virus or a microbe with a DGR, you gamble every time you mutate. But, perhaps, …
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High Five: Celebrating the JGI-UC Merced Genomics Internship Program
… Zhong Wang and Science Programs Deputy Axel Visel teamed with University of California (UC), Merced assistant … of the fifth summer of its flagship education program with UC Merced. JGI Director Nigel Mouncey and program organizers Wang, Visel and Sindi, along with UC Merced Undergraduate Research Opportunities Center …
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Virus Discoveries that Keep Getting Bigger
… , diversity exists in infectious cycles, as well, with viruses relying on different strategies for initiation, … reference genome, to sift for snippets of giant viruses in metagenomes. This has been useful in marine environments, … A fourth option for virus discovery is reconstructing metagenome-assembled genomes through metagenomic binning. So …
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Secrets of the Needles: What Microbes do on Conifer Leaves
… land and the atmosphere. Microbes living there can interact with chemical defenses of plants and influence nutrient … composition varied across both sites and host tree species, with geographic site exerting the stronger influence. … the analysis of mobile genetic elements across all of the metagenomes. Learn more about her time at the JGI here . …
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RECAP: Keynote Speakers Talk Innovation at 2022 JGI Annual Meeting
… our  2022 Annual Meeting . The meeting was a hybrid event, with guests joining onsite at the Integrative Genomics … , Weizmann Institute of Science One cell can change large-scale processes Keynote Talk Title: Host-virus dynamics in … vast algal blooms. Their work takes a view across many scales: from natural blooms in the ocean, down to smaller, …
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Taking Stock of the Known and Unknown Microbial Space
… Dongying Wu, a member of the Functional Annotation team within the JGI’s Microbiome Data Science group. “Turns out … genes on nearly 2 million genomes, including isolates, metagenome-assembled genomes (MAGs) with varying quality … scores representing potential genomes, and nearly 44,000 metagenomes. All of the data are publicly available in …
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