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Streamlining Regulon Identification in Bacteria
… RIViT-seq technology could speed up associating transcription factors with their target genes. The … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … Nature Communications on June 17 , 2022, was conducted by JGI Director Nigel Mouncey and research scientist Hiroshi …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… The Science Soil bacteria in the genus Streptomyces are nature's chemical factories. They hold genetic blueprints for … of multiple omics data from various environments — that JGI users can leverage to create a more complete picture of … with the Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user facility located at …
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2025 Progress Report
… JGI researchers demonstrate how their laboratory and data science efforts support users, advance foundational …
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A Community Resource for Secondary Metabolite Researchers
… The Secondary Metabolism Collaboratory encourages user engagement. The Science In addition to … The U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … from isolate and metagenome data.   The SMC ( smc.jgi.doe.gov ) is designed with two main objectives. First …
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Benjamin Cole
… by altering their growth program, and on how plants coordinate their gene expression with light and temperature oscillations throughout the day. At the Joint Genome Institute, … Implementation of the Index of Cell Identity as an R package … Education … Selected Publications …
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
… Researchers looked across many organisms to see that aminotransferase enzymes have evolved mix-and-match … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … for computational analysis of the AT enzyme family, the JGI provided DNA synthesis capabilities to enable functional …
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Finding the Fermenters
… Harnessing BER-funded data resources, researchers built an interactive and … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … metabolism from the literature. They then used the JGI’s GOLD and IMG data portals to get information about the …
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Busting the Unbreakable Lignin
… plant for energy: Cellulose, hemicellulose and lignin, cumulatively called lignocellulose, are the primary components of … Research Center. O’Malley is also affiliated with JBEI. The JGI data portals and pipelines helped identify potential genes responsible for lignin deconstruction. (The JGI also conducted RNA sequencing and alignment to the …
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An Automated Tool for Assessing Virus Data Quality
… can help researchers assess virus sequence fragments and data quality. The Science Through advances in sequencing … uncultivated viruses. Following up on those guidelines, JGI researchers have now developed CheckV (pronounced … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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Iron-rich Microbial Mats’ Main Players: Marsarchaeota
… in early Earth conditions. The Science Through a combination of sequencing tools and techniques applied to samples … into the evolution of life on Earth. For decades, longtime JGI collaborator Bill Inskeep of Montana State University … caused by the presence of iron led Inskeep and his colleagues to name the archaeal lineage for the planet Mars. To …
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Making a Lichen Together
… Science The humble lichen is a superorganism: one being that is actually comprised of two (or more) participants. One … in  BMC Genomics . To explore the genomes, Armaleo and colleagues worked with Igor Grigoriev, the Fungal & Algal Program … the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility. Grigoriev and …
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How Maize Makes An Antibiotic Cocktail
… Maize produces a family of compounds that protects it against infections — using surprisingly few … as  Sorghum bicolor — a  candidate bioenergy feedstock and  JGI Flagship Plant — could produce at least 15 zealexins. … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, through its  …
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