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…   The Human Genome Project began in 1990 when the U.S. Department of Energy (DOE) partnered with the National … genome. They were interested in genes involved in repair of DNA damage, and those associated with atherosclerosis and … with the HudsonAlpha Institute for Biotechnology.   Publications Grimwood, J., Gordon, L., Olsen, A. et al. The …

… Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel … laboratory conditions, their genomes can’t be sequenced using traditional approaches. Identifying and characterizing … acknowledge the significant efforts to collect and extract DNA from these samples, many of which come from unique, …

… Understanding the shared genetic toolkit of ancestral and … on the full composition of genes, or pangenome, of the model plant  Marchantia polymorpha. Commonly known as … to their environments, two gene families—peroxidases and nucleotide-binding leucine-rich repeats (NLRs) —stood out …

… Developing and validating an integrated approach to genome … developed and improved upon a tool that combines existing DNA sequence binning algorithms, allowing them to … and soil from the Angelo Coast Range Reserve in California. Using DAS Tool on data from soil samples, researchers were …

… JGI researchers lend expertise to develop tools and data hub for NIH program. While the … Way, viruses outnumber the microbes by at least another order of magnitude. For years, scientists at the DOE Joint Genome Institute, … The U.S. Department of Energy Joint Genome Institute, a DOE Office of …

… Collaborations for User Science (FICUS) program, two Department of Energy (DOE) Office of Science national user … offering insights into how algal ponds can regulate photosynthesis under fluctuating environmental conditions. The … computational resources with JGI’s cutting-edge genomics, DNA synthesis and complementary capabilities. Because the …

… to sequence and assemble, in turn limiting the use of modern, genomic breeding in these crops. For diploid species, … successfully assembled a first monoploid reference sequence using a targeted approach that focused on the gene rich part … artificial chromosomes (BACs), vectors that can hold large DNA segments such as an entire sugarcane gene and its …

… at the JGI and the Bigelow Laboratory for Ocean Sciences described a novel technique to access high-quality genomic information using minute quantities of DNA derived from individual environmental cells. The proof …

… oceans. Through the Community Science Program of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a … accepted proposals, said Susannah Tringe, JGI User Programs Deputy. “These new CSP projects accelerate our efforts to … are believed responsible for a fifth of the planet’s photosynthesis activities. Aside from being a key component of …

… microbiology and ‘omics techniques to experimentally determine that Nanohaloarchaeota are symbionts, rather than … ecological consequences of microbe-microbe interactions. Using metagenomes recovered directly from environmental … region in the SPEARE proteins appears to be involved in DNA degradation, and these proteins may be directly involved …