Search

… synthesis support, sequencing, integrative -omics, and data mining, empowering research collaborators to take on … screens for characterization of new enzymes and use the data we generated to train machine learning models now …

… how to sharpen the CRISPR-Cas9 tool for a non-conventional eukaryotic host — an approach, the team says, that could be …

… and chemistry for advanced analysis, modeling, and data integration. Dr. Bowen’s expertise in spectral … Northen, T., & Bowen, B. (2015). Analysis of metabolomics datasets with high-performance computing and metabolite … important ions and positions in mass spectrometry imaging data using CUR matrix decompositions. Analytical chemistry, …

… cells of the uncultivated SAR324. The constellation of data gave the team unprecedented resolution to study the … SAR324 on IMG/M Data portal … tools designed for analysis of DNA and RNA sequence data.  … Datasets …

… and the atmosphere. The team learned that some bacterial families carry genes for degrading monoterpenes such as …

… to link experimental evidence across species. Centralized databases with large-scale transcriptome projects such as … is an updateable resource. To demonstrate that, we included datasets from two species, one of which is sweet sorghum Rio … genes. It provides detailed functional annotations, protein homologs, plant family information, and a genome …

… specifically for generating libraries of large gene families to understand enzyme activity. As another early … or improving bioinformatics tools that can help with dataset analysis, as well as how they can be shared with and …

… a similar type of search in microbial and metagenomic databases. In this case, the machine “learned” to identify a … should be classified as an order of viruses, with six families. Additionally, the team uncovered a range of … diversity among inoviruses with more than 3,400 different proteins, many linked to key functions such as virion …

… research focuses on leveraging thousands of metagenomic datasets from host-associated and environmental samples to … She also leads the DOE’s multi-lab National Microbiome Data Collaborative (NMDC). Prospective users with questions … Wood-Charlson EM, et al. 2020. The National Microbiome Data Collaborative: enabling microbiome science. Rev. …

… and products . A minimum request of 1 Tb of sequence data is required to qualify for BERSS. For DNA synthesis … This Center also has a major focus on sustainability, examining the environmental and socioeconomic implications of … science.  Projects include de novo generation of genome data, assistance in interpreting and/or building on an …

… the team then used DNA synthesis and cloning, followed by protein in vitro expression and mass spectrometry-based …

… to extract meaningful biological insights from sequence data, employing IMG data and tools for comparative analysis, visualization and interpretation using public datasets.  … distribution of prokaryotic microbial genome and microbiome datasets. It includes JGI-sequenced and publicly available …