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Better Genome Editing for Bioenergy
… part of CRISPR-Cas9 technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a powerful, high-throughput gene-editing tool that can help scientists engineer organisms for bioenergy applications. Cas9 needs guide … This work was supported by DOE Joint Genome Institute grant  CSP-503076 (IW, HA, and MB) and …
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Len Pennacchio
… In 2003, Dr. Pennacchio joined the DOE Joint Genome Institute and has focused on applying state-of-the-art … Genomic Technologies. oClick to learn more about the offerings and capabilities we offer JGI users to help advance … of Genomic Technologies serves as the JGI’s primary point of contact for all High-Throughput Data Generation …
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Streamlining Regulon Identification in Bacteria
… RIViT-seq technology could speed up associating transcription factors with their target genes. The … that can be turned on or off by the same regulatory protein. Researchers demonstrated the efficacy and potential of regulon identification by in vitro transcription-sequencing (RIViT-seq) to facilitate …
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A Better Way to Find RNA Virus Needles in the Proverbial Database Haystacks
… Team develops a computational pipeline to sift and characterize RNA virus sequences.  A zoo once offered a coloring book featuring polar bears in winter scenes that came with crayons in … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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Kjiersten Fagnan
… Kjiersten Fagnan began working with JGI in 2012 as a NERSC bioinformatics computing consultant, after completing a … Kjiersten Fagnan is the JGI's Chief Informatics Officer. Click to learn more about how the JGI supports the entire data life cycle through resources including the JGI portals, and our broader data ecosystem. …
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Trent Northen
… is currently a Senior Staff Scientist at Berkeley Lab. Since joining Berkeley Lab in 2008, Dr. Northen has had leadership … to learn more about the program's areas of focus, major initiatives and more.  … B.S. in Chemical Engineering, University of California Santa …
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DAS Tool for Genome Reconstruction from Metagenomes
… Developing and validating an integrated approach to genome recovery from metagenomes. The Science Through the JGI’s Emerging Technologies Opportunity Program (ETOP) , researchers … The work conducted by the U.S. Department of Energy Joint Genome Institute is supported by the Office of Science …
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JGI Earth Month: The Unusual Metabolism That Helps Plants Withstand Drought
… In April 2020, we mark both the 50th celebration of Earth … Earth and DNA are close to our JGI hearts, we’re highlighting genomic science research that feels especially relevant to living on a changing planet. Transcript for Audio   ALISON:  … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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Toward More Reproducible, Reusable Stable Isotope Probing Experiments
… with the prospect of meta-analyses boosted by AI and Machine Learning — JGI researchers and collaborators work to create FAIR … advances. Over the last two decades, Stable Isotope Probing (SIP) has opened vast windows into specific activities … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User …
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Extracting the Secrets of Secondary Metabolites
… for survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and CRAGE technologies. While CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is the leading tool … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science User Facility, …
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2024 Progress Report
… The Integrative Genomics Building (IGB) seen above is home to the DOE Joint Genome Institute (JGI). Researchers from the DOE Systems … who made use of our data. We completed 39,870 projects in FY24 We generated 871 Terabases of sequence We … advanced genomic capabilities. This year we brought online the latest short-read technology, the Illumina NovaSeq X …
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VEGA Symposium
… – $250 Students & Postdocs – $200 Regular Rates (begin September 19, 2026) General & Berkeley Lab Attendee – $300 Students & Postdocs – $250   Hosted by the DOE Joint Genome Institute, the 5th Viral EcoGenomics and Applications (VEGA) … VEGA 26 will take place at the UC Berkeley MLK Building, in the East Pauley Ballroom, November 18–19, 2026. The …
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