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… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … the science and scientists of secondary metabolism.  DAN: Welcome back to Natural Prodcast! This is episode 4! From … bacteria, of course, are much smaller. But I think a lot of groups are sequencing fungi. Just going and sequencing them. …

… Maize produces a family of compounds that protects it against infections — using … called terpenoids, which have a structure belonging to a group of chemicals called terpenes. Terpenes are important … would also act on native substrates to produce additional novel antibiotics. Summary The zealexins are chemically …

… By characterizing the structure and function of a methylthio-alkane reductase system, researchers could … in point: for us, the smell of the ocean simply signals we’re near the beach. For bacteria, that salty, slightly … of this work.  North led the team that did this work. His group from the Ohio State University joined Hannah Shafaat’s …

… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that … and pharmaceuticals. The team at Merchant’s lab also discovered the existence of polycistronic genes within … C. zofingiensis on Phytozome …

… When the JGI Data Portal (https://data.jgi.doe.gov/) … through the plant portal  Phytozome . Now the portal offers a way for users to more easily access public data … of metadata. For Steve Wilson, JGI’s Systems Engineering group lead, the Data Portal reflects a structural shift in …

… Twice a year, the DOE Office of Science Graduate Student Research (SCGSR) program … User Programs deputy and head of the Microbial Systems group. Tringe’s research group focuses on the roles of … of Texas-Austin. Rambo will be studying the influence of viruses on carbon cycling in coastal mangroves. The work …

… A group led by JGI scientists have made strides in improving … ( CRAGE ). CRAGE enables scientists to insert large pieces of DNA (up to 60 kb) in a single step, directly into the … used CRAGE to engineer domesticated bacterial strains with novel biosynthetic gene clusters (BGCs). BGCs make diverse …

… A special issue of Synthetic Biology celebrates research enabled by the JGI … Science Program, which started in 2012, and what they’ve discovered through their collaborations. One review article … in establishing larger-scale research projects in our group. It’s enabled us to accelerate gene, enzymes, and …

… Hao Chen, Jay Chen, Maureen Coleman and Hugh Cross; [Below] Zac Freedman, Martin Jonikas, Lotus Lofgren, Fumito Maruyama, Lauren Stadler, Tingting Xiang and … opportunities for biomanufacturing, from industrial enzymes discovered in extreme environments to engineered microbiomes …

… JGI's Simon Roux describes the structure and content of the IMG/VR v3 database (img.jgi.doe.gov/vr), the latest … assembled from metagenomes. He also demonstrates briefly how to leverage novel capabilities of IMG/VR to browse and search through …

… For many scientists, the culmination of their work into a written report that is published in a … dating over a billion years old. It’s an insanely diverse group of organisms that include some delicious additions to … band together to build proteins. What Wint and her mentors discovered in the genomes helped to reinforce Charles …

… Ancient  Chloroflexota s ditched their flagella and other traits when migrating back to the ocean. The Science Scientists have discovered flagella in an unexpected place: hot … The work (proposal:  https://doi.org/10.46936/10.25585/60000691 … ) conducted by the U.S. Department of Energy Joint Genome Institute …