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Extracting the Secrets of Secondary Metabolites
… for survival, may now be easier to characterize following a proof-of-concept study in which researchers paired … to integrate large genetic payloads directly into diverse microbes. Combining CRAGE with CRISPR provides researchers … researchers are no longer limited to using model host microbes; theoretically, any microbe can serve as the …
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RECAP: Keynote Speakers Talk Innovation at 2022 JGI Annual Meeting
… The JGI was honored to host some of the brightest minds in genetics as part of our  2022 Annual Meeting . The … . Assaf Vardi , Weizmann Institute of Science One cell can change large-scale processes Keynote Talk Title: Host-virus … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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Identifying the Microbial Cleanup Crew at a Superfund Site
… Analysis reveals the microbial community involved in a bioremediation effort. The Science In 1999, … to bioremediation efforts for decades. Identifying resident microbes that can help bioremediate toxic substances has led … (ERD.) It is dependent on the presence of the existing microbes in the groundwater and adjusting the environmental …
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A Natural Mechanism Can Turbocharge Viral Evolution
… Understanding how a fundamental mechanism of evolution allows microbes to adapt to changing environments. The Science The … of how a fundamental mechanism of evolution — DGRs — allows microbes to adapt to changing environments. It also sheds … The work conducted by the U.S. Department of Energy Joint Genome Institute is supported by the Office of Science …
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Model Fern Reveals Insight into DNA Thievery in Ferns
… with C. richardii The Science Fern genomes are huge, and incredibly complex — making it difficult to grasp a deeper understanding of … show a long history of dynamic evolution and rapid changes in both genome content and structure following a … The work conducted by the US Department of Energy Joint Genome Institute is supported by the Office of Science …
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iPHoP: A Matchmaker for Phages and their Hosts
…   To understand virus-host dynamics, computation helps fill in what cultivation can’t. The Science At first, viruses are … to commandeer. For bacteriophage viruses, these hosts are microbes like bacteria, not humans. With metagenomic … Within the domains of archaea and bacteria, millions of  microbes govern ecosystems. These organisms carry out …
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Ben Bowen
… Specializing in mass spectrometry-centered projects, Dr. Bowen’s work focuses on developing high-performance computing workflows and integrating mathematics and chemistry for … BS – University of Arkansas, Fayetteville, Chemical Engineering Ph. D. – Arizona State University, Tempe, Chemical …
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Benjamin Cole
… Dr. Cole is interested in studying how plants interact with their environment. Prior to … Dr. Cole’s research focus has been on understanding how microbes can colonize plant roots, focusing on genetic … of California, San Diego (PhD, 2011) Rensselaer Polytechnic Institute (B.S., 2006) …
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Trent Northen
… is currently a Senior Staff Scientist at Berkeley Lab. Since joining Berkeley Lab in 2008, Dr. Northen has had leadership … to link genomes with environments to understand how webs of microbes cycle carbon and sustain biomes via the development … to learn more about the program's areas of focus, major initiatives and more.  …
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How Filamentous Fungi Sense Food
… Tracing gene regulatory networks in the model fungus  Neurospora crassa . The Science A team … Neurospora crassa, and to identify and decide on the order in which this fungus breaks down plant cell wall materials … We acknowledge the use of deletion strains generated by Grant P01 GM-068087 “Functional Analysis of …
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Boosting Small Molecule Production in Super “Soup”
… Do metabolic pathways from engineered yeasts still work in cell-free environments? … for the past year and a half, “the logistics haven’t changed,” noted Northwestern graduate student Blake Rasor. … metabolic performance, Alper noted. “This was really an unknown exercise,” he added. “It wasn’t a proven premise …
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Here, There and Everywhere: Large and Giant Viruses Abound Globally
… the global diversity of large and giant viruses. While the microbes in a single drop of water could outnumber a small city’s … genome tree of viral diversity – yet.” “We expect this to change with not only new metagenome datasets becoming … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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