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… PacBio? A(nswer):  Regular PacBio typically requires ~ 1.5-10 ㎍. Low-input protocols are continuously improved, but … involves PCR amplification of the library. 6mA and 4mC (~50x depth), 5mC (~250x depth required). Methylation detection currently …

… (CAMI) Challenge, a competition launched in 2015 by a community initiative, with varying numbers of genomes … to tackle metagenomes with low (40 genomes) to high (596 genomes) complexity. The environmental datasets included … were able to reconstruct 79 minimally contaminated (<5%) draft genomes to >70% completeness. Of those 79 genomes, …

… by the NSF Dimensions of Biodiversity Program (DEB-1542509 to S.D., DEB-1542486 to LBS, and DEB-1542599 to … Natural Science Foundation of China (31590821, 31561123001, 31500502, 41871044), National Key Research and Development …

… dhesion and  r estriction  e ndonuclease domains—of up to 8,500 amino acids in length. These were actively synthesized … work was supported by the Australian Research Council (DP150100244) and the Australian Antarctic Science program … the US Department of Energy under contract no. DE-AC02-05CH11231. S.E. was supported by the EMBO Long-Term Fellowship …

… of the U.S. Department of Energy under Contract No. DE-AC02-05CH11231. The collection of the M. sinensis and M. …

… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of … completed by the JGI. It has since been cited more than 5,400 times, including a number of projects that point to … due to the sequence’s availability via Phytozome. In 2015,  a new and revised version brought the soybean sequence …

… research following the discovery of bacteria 5,000 times the average size. Woyke’s  Single Cells Group … Database (GOLD ) database that also marked the platform’s 25th anniversary, published in  Nucleic Acids Research .  … sequences, initially using it to comb through more than 5,000 data sets and thereby increasing RNA virus diversity …

… The work (proposal:  https://doi.org/10.46936/10.25585/60000936 ) conducted by the U.S. Department of Energy … Department of Energy operated under Contract No. DE-AC02-05CH11231. …

… 2 interns in the summer of 2014 has grown to a total of 75 with the inclusion of the 2023 cohort. Each of them has … helped her in her role at the Lab as well.  One of the 2015 program alumnus Cristhian Gutierrez discussed how his time …

… to the global research community.  Published January 17, 2025 in Science Advances , researchers at the U.S. Department … , the team found that isolate genomes represent only 6.55% while MAGs account for about 57% of the estimated …

… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of … is interesting because in humans (where it’s called RECQL5), the loss of this protein is associated with cancers. …