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A Better Way to Find RNA Virus Needles in the Proverbial Database Haystacks
… Team develops a computational pipeline to sift and characterize RNA virus sequences.  A zoo … Computational Sieves to Filter Sequences There are more microbes on the planet than particles in a handful of dirt, … all across the world and lead to cell death and/or profound changes in the cell physiology during infection.” While all …
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A Community Resource for Secondary Metabolite Researchers
… Collaboratory encourages user engagement. The Science In addition to the core set of "primary metabolites"—chemical compounds shared by most living creatures for energy, growth and reproduction—most … more than 13 million BGCs in the catalog at the time of publication, it is the largest repository of BGC sequence …
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Innovative Technology Improves Our Understanding of Bacterial Cell Signaling
… Newly developed chemiluminescent biosensors shed light on how bacteria function and … also regulates enzymes involved in cellulose production in microbes, these biosensors may eventually lead to ways to … Additionally, it opens the door to measuring real-time changes in cyclic di-GMP via live cell imaging. Summary From …
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JGI Early Career Researchers Featured in mSystems Special Issue
… In a special issue of mSystems , out May 14, 2019, JGI … outline more targeted approaches to reconstruct individual microbes in an environmental sample beyond the … into several small pools before sequencing to recover rare microbes. The technique was applied to a recent Nature …
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Yasuo Yoshikuni
… has been head of the DNA Synthesis Science Program since 2015. The mission of this program is to harness the power of DNA synthesis, strain engineering, and biosystems design for DOE-mission-relevant … to learn more about the program's areas of focus, major initiatives and more.  …
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JGI@25: Cow Rumen and the Early Days of Metagenomics
… In honor of the JGI's 25th anniversary in 2022, we have … Oh, the magical world of the cow stomach. Rumen – and its microbes – are really a powerhouse. Rumen microbes have the ability to break down hardy plant cell …
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The Expanding Universe of Methane Metabolisms in Archaea
… Metagenome-assembled archaeal genomes provide new insights into an ancient metabolism. Methane is a greenhouse gas 20 … of the Earth’s atmosphere and regulating the global climate for life to flourish. For Guillaume Borrel and … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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Secondary Metabolites Program
… growth, provide critical advantages to the organisms producing them, and are often involved in defense, nutrient acquisition and communication. Studying … algae and plants. These compounds are key to organisms' interactions with their environments and with each other, …
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Igor Grigoriev
… Dr. Grigoriev joined the JGI in 2003, following his postdoctoral training at UC Berkeley and work in the … to learn more about the program's areas of focus, major initiatives and more.  … BA/MS in Biophysics, Moscow Engineering Physics Institute, Moscow, Russia PhD in Molecular …
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Axel Visel
… Dr. Visel joined the DOE Joint Genome Institute in 2010. As the Deputy for Science Programs, he focuses on … our seven science program — their areas of focus, major initiatives and more.  … formulation and implementation of scientific policy, engaging in interactions with the scientific community at large. …
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Danielle Goudeau
… Danielle operates the single-cell genomics pipeline for JGI collaborators. This work combines custom flow cytometric analysis, cell sorting, genome … flow cytometry protocols for targeted recovery of specific microbes. …
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Data Ecosystem
… The JGI is leveraging its current partnerships to offer new capabilities and … different organizations is discoverable and accessible. Linking the resources of powerful institutions like the JGI, … (ESNet), the JGI has unique access to both expertise and infrastructure to facilitate these efforts. Particular areas …
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