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Gene Expression: From On-Off Switch to Dial
… Fine-tuning metabolic gene expression helps identify variants … to expression, scientists can now opt for various shades of grey. The ability to fine-tune the level of gene expression allowed researchers to identify … This work was funded by the Air Force Office of Scientific Research under Award No. …
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Marine Microbe Contains Multitudes
… A deep dive into microbial genomics reveals one bacterial species is made of four ecologically distinct groups with different … to the blue-lit twilight zone, to the continuous pressure of the dark abyss, 4000 m (2.5 miles) deep. Scientists have … #3777 (to EFD). The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… With a new methodology, scientists are now getting more complete genomic results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the microbiome of the earth, but most species do not grow easily in the …
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iPHoP: A Matchmaker for Phages and their Hosts
…   To understand virus-host dynamics, computation helps fill in what cultivation can’t. The Science At first, viruses are … With metagenomic sequencing, researchers have found more of these viruses than ever before, in all kinds of ecosystems. However, matching these viral genetic …
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New and Improved: Eucalyptus Reference is Now Accessible
… An improved genome assembly to support targeted tree breeding for the bioeconomy.   The Science Researchers report a new reference genome for eucalyptus in the July edition of the journal G3 Genes | Genomes | Genetics , with … both haplotypes, meaning it separately represents the sets of chromosomes inherited from each parent. It also has …
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Defining a Pan-Genome for Antarctic Archaea
… Analysis of haloarchaeal metagenomes broadens understanding of Antarctic biogeography. The Science Haloarchaea flourish … (project 4031). The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science User Facility, …
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Team Science Reveals Important Protein in Poplar
… Knockout experiments showcase potential for engineering bioenergy crops The Science Scientists at … Described as the “DOE Tree,” poplar is considered one of the  Flagship Plants for the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office …
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Identifying the Microbial Cleanup Crew at a Superfund Site
… Analysis reveals the microbial community involved in a bioremediation effort. The Science In 1999, … PCE (perchloroethylene) found its way into the groundwater of several communities in New Mexico via leakage from a … bioremediate toxic substances has led to the development of cost-effective environmental cleanup strategies. Summary …
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Mining Metagenomes for Cas Proteins
… Cas14 proteins discovered from JGI’s IMG/M database and biochemically … Institute.  The Science Researchers report the discovery of miniature Clustered Regularly Interspaced Short … Integrated Microbial Genomes and Microbiomes (IMG/M) suite of tools managed by the U.S. Department of Energy (DOE) …
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Benjamin Cole
… Dr. Cole is interested in studying how plants interact with their environment. Prior to joining the Joint … University of California, San Diego (PhD, 2011) Rensselaer Polytechnic Institute (B.S., 2006) … List of pubs available on NCBI … Implementation of the Index of Cell Identity as an R package …
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Getting to the Bottom of Fungal Functions Across Earth’s Forests
… between fungal guilds, genes and function. If a tree falls in the forest — whether or not anyone registers the sound — one thing is for sure: there are lots of fungi around. Within a forest’s soil, hundreds of species decompose debris, mobilize nutrients from that …
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Expanding Virophage Diversity
… are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant viruses. Virophages … in  Microbiome , researchers from the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science facility, have increased the number of …
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