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… A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in … tool will make the right cut, researchers created a set of guide RNAs that were effective against 94 percent of the … and his advisor Ian Wheeldon, a chemical engineer at the University of California, Riverside. The team also included …

… microbial genomics reveals one bacterial species is made of four ecologically distinct groups with different … community genomes and expressed gene transcripts (metagenomes, metatranscriptomes), as well as the genomes of … — then a postdoctoral associate in Ed DeLong’s group at the University of Hawaii at Manoa — and colleagues were able to …

… validating an integrated approach to genome recovery from metagenomes. The Science Through the JGI’s Emerging … been utilizing metagenomics as a way to study a collection of hard-to-culture microbes, but the efficacy of this … team led by longtime JGI collaborator Jill Banfield of the University of California, Berkeley and involving JGI …

… Miscanthus  sequence offers insights into benefits of polyploidy and … The Impact Among the long-term aims for bioenergy feedstock crops are increasing their yields and improving … across Europe and Asia. CABBI partners include the University of California, Berkeley and the HudsonAlpha …

… Maize produces a family of compounds that protects it against infections — using … plant, such as  Sorghum bicolor — a  candidate bioenergy feedstock and  JGI Flagship Plant — could produce at least … study’s senior author Alisa Huffaker, a biologist at the University of California, San Diego. The findings could help …

… Sequence-based studies — from metagenomics to single-cell work — have quickly accelerated understanding of giant viruses. The Science In the last thirty years, in … National Laboratory (Berkeley Lab), and Aix Marseille University located in Marseille, France, leverage their …

… Novel study looks at microbiomes in aerial surfaces of plants and their roles in plant health and environmental … microbiomes. Scientists conducted a shotgun metagenomic survey on three types of conifers–limber pine, … a project supported by the JGI Community Science Program, University of California (UC) Merced scientists conducted a …

… Twice a year, the DOE Office of Science Graduate Student Research (SCGSR) program awards … SCGSR awardee, Ian Rambo from Brett Baker’s lab at the University of Texas-Austin. Rambo will be studying the … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …

… A workflow for capturing the genetic make-up of specific uncultivated microbes from complex environmental … of the microbial world through bulk community sequencing (metagenomics) and single-cell genomics, the vast majority of … allow researchers to focus on specific microbes within metagenome samples and associate their sequences with their …

… before. In 2006, the JGI produced 33 billion base pairs of sequence; by 2023, that number was almost 717 trillion. … to enable large-scale analysis. The story of a massive metagenome assembly for a time-series experiment from the … been sampling microbes at Lake Mendota, which borders the University of Wisconsin-Madison, for over 20 years in order …

…   Each year, the JGI accepts proposals for state-of-the-art functional genomics research from potential users … synthesis and omics capabilities to enhance understanding of gene and genome function.  Below find a list of the six researchers accepted for 2023. Proposals are …