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… Leveraging massive comparative genomics to decode millions of mystery genes and lay a future-ready foundation     Over … about 200,000 fungal species have been named. Among those sequenced, roughly half of all genes have completely unknown … The U.S. Department of Energy Joint Genome Institute, a DOE Office of …

… DAN: You’re listening to the US Department of Energy Joint … you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …

… The mission of the Joint Genome Institute is to serve the scientific community as a user facility pioneering functional genomics to solve the … The researcher then submits a proposal for consideration in the next … as needed), and the work plan is written into a Statement of Work document. …

… The JGI’s DNA Synthesis Program supports a wide range of projects, from single-gene … The DNA Synthesis Program plays a central role in advancing … project. These advancements contribute to the development of new biofuels and sustainable biochemicals. The DNA … Program aims to generate large datasets to explore sequence-function relationships, advancing the discovery of …

… DAN UDWARY: Hey, everyone! Welcome to the “Self Promotion … is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a …

… Across four forests, researchers have leveraged data from … registers the sound — one thing is for sure: there are lots of fungi around. Within a forest’s soil, hundreds of species … at Lawrence Berkeley National Laboratory (Berkeley Lab) sequenced 1 trillion bases — a terabase — of soil RNA for …

… DAN: You’re listening to the US Department of Energy Joint … DAN: Alright, so I think we’ve covered a little bit about why they’re important. But one of the things I did want to … live in the root nodules of plants. And these guys were sequenced, and you can see that different Frankia have …

… Dan Udwary: You’re listening to the Department of Energy … about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean …

… DAN UDWARY: Hey everyone and welcome back to a new session of … And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, …

… The JGI’s data stewardship expertise and infrastructure enable a broad community of scientists and engineers to leverage our data to develop new algorithms, models and tools in support of DOE mission priorities. Data discoverability and … Download plant, algal, fungal and microbial genomes and …

… DAN UDWARY: Hey, everyone. I’ve got a great episode for you … learned a lot so much history from this conversation about why the ocean was basically unexplored until the 70s, and … forward to seeing the data when it finally gets off the sequencers. The pandemic has obviously slowed JGI down a …

… The Joint Genome Institute and the Molecular Foundry have launched a joint Critical Minerals and … for researchers to request the capabilities and expertise of both national user facilities in one research proposal.  … Access to the Molecular Foundry and use of JGI capabilities …