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Wang M, Lim J, Tice H, Daum C, Xu J, Northen T, Visel A , Bristow J, Niyogi KK, Wei CL (2015). Lineage-specific … M, Wright C, Afzal V, Simpson PC, Rubin EM, Black BL, Bristow J, Pennacchio LA*, Visel A * (2012). Large-scale … Tringe SG, Visel A , Woyke T, Wang Z, Rubin EM (2011). Metagenomic discovery of biomass-degrading genes and genomes …
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That is one of the really big frontiers for the next stage of natural product drug discovery I think. Or even … computational skills among biologists JGI CSP Proposal: Metagenomic mining of natural product diversity and …
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… the idea that you could go internationally to do the next stage of your training and that there might be more to be … how best to begin. And so in the end, we did it in several stages. So we started out internally by making a list on the … a sort of front end tool, so it’s being used as the first stage in discovery. There are so many different ways that you …
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… in an obvious way. NIGEL MOUNCEY: We did a little bit of metagenome screening work and did find related clusters. But … in the environment and how we might be able to take advantage of those to improve plant health, for example. DAN: … is going to be fully virtual because we’re not at the stage yet where I think everybody feels comfortable in …
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… nature does this with such elegance And also to take advantage of the biological properties that these molecules have … to test that hypothesis through site-directed mutagenesis, we would end up with dead enzymes. So often, when …
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… a mixture of, for example, metatranscriptome sequencing, metagenomics, single cell genomics. We even do the flow … for you, we sequenced thousands for you or thousands metagenomes. And I think also the quality that we provide. So … also have a lot of analysis pipelines, be it for, again, metagenome, metatranscriptomes for SNP analysis if somebody …
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… by chemical synthesis and make analogs in combination of mutagenesis and direct evolution. Yeah. DAN UDWARY: So it’s …
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… a more systematic picture through single-cell and metagenomic sequencing. A team co-led by Mária Džunková, … the virus in 34 hosts or 26 percent of the single cells. Metagenomics sequencing then allowed the team to ask, for the … the strategy of lysogeny. The ability of the virus to tag along with the host has earned this strategy a riff, …
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