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… in natural products as an undergrad. So for me, it was studying sort of the interface of chemistry and biology … me. And I could combine my passions in different areas to study how these molecules made, how do you test the … of Utah , about her secondary metabolism research on novel microbes and bioactive compounds in the Great Salt Lake. …
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… and synthetic biology. But also the metagenomics and gut microbiome, as I think that it’s like a perfect storm in … the production of the natural product. So that was my PhD study, and then towards the end of my PhD study, then recombinant DNA technology was becoming …
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… like, and then you could characterize it. The classical study that demonstrated this is Challis et al, Chemistry and … some marine. There’s some soil samples. There’s human gut samples. There’s lots and lots of– animal associated, … what kinds of gene cluster families are in which kinds of orgasms. And so we have all of that information. We have …
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… processes, development of high performance plants and microbes, and understanding microbiome interactions. The … insights into how small molecules function within plants, microbes, and ecosystems. Identifying and analyzing primary … range of biological and environmental samples — including microbes, fungi, plants and soils. Through a combination of …
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… advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … to assess microbial activity across ecosystems. By studying microbial communities and their interactions, the … and many other applications. By understanding how microbes contribute to ecosystem functions, the Program …
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… And for the audience, ethnobotany is the scientific study of the ways that people interact with plants, whether … and take soil and discover a new important drug from the microbes in that soil, there are now international … in many different cultures. And just because you do a field study in a location doesn’t mean that you’re going to have …
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… was looking to develop new methods for DNA sequencing of microbes. And what kept breaking our methods was these damn … And another thing is the bugs that produce them – the microbes that make these secondary metabolites – are usually … just to back up, because you started talking about the microbes that produce these secondary metabolites, like, …
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… And these were not in natural products, these were in studying regulatory mechanisms of, first, E. coli and then … build out much more of an integrative genomics approach to studying environments, studying organisms, to looking at … But they really span our core science programs which are microbes, and fungi, and algae plants, synthetic biology. …
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… effects. ALISON: Yeah, I guess you’d use something like a gas chromatographer. Yeah. DAN: Yeah. So that involves …
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