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… DAN: You’re listening to the US Department of Energy Joint … lot of like synthetic chemistry effort to create a bunch of novel compounds that actually didn’t pan out. DAN: And there … of molecular biology got more sophisticated around the 80s and the 90s. And so we started to be able to explore DNA …

… The Facilities Integrating Collaborations for User Science (FICUS) call represents a unique … provides customized analysis, the JGI also participates in publication of results. … Proposals for the annual FICUS call with EMSL begin with a Letter of Intent … After an LOI is accepted, the researcher then submits a …

… The Facilities Integrating Collaborations for User Science (FICUS) initiative was … provides customized analysis, the JGI also participates in publication of results. … All proposals undergo technical review by JGI staff as well as staff … What happens after I submit? …

…   Visualizing a novel, candidate viral genome found in the deep subsurface … are carbon-fixing microbes and targets of multiple viruses in Earth’s deep subsurface. They are abundant … are abundant and dominant populations in oxygen-poor environments without oxygen deep below ground. These archaea fix …

… Dan Udwary: You’re listening to the Department of Energy … time called Genbiotics , which was a large program to find novel antibiotics. And this particular project focused … then I contacted a number of PIs, and in the end, I think 80 research groups from around the world contributed with, …

… The Joint Genome Institute and the Molecular Foundry have launched a joint Critical Minerals and Materials … Access to the Molecular Foundry and use of JGI capabilities is free. The JGI supports remote … The program seeks user proposals that integrate genomics with …

… DAN: You’re listening to the US Department of Energy Joint … And then, you know, they will have to create an environment that’s good for them to grow in. They might have … often use primary metabolites as building blocks to produce novel molecules. And so we’ve got glycosides being made into …

… Microbial cells infected by viruses undergo metabolic reprogramming. The Science If it … Berkeley National Laboratory (Berkeley Lab), and the  Environmental Molecular Science Laboratory (EMSL), a DOE Office of … A portion of this research was performed under the …

… Every approved proposal starts with a User Agreement — before any work can begin, … rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is … After your proposal is approved, the Contracts Officer will send required …

… DAN: You’re listening to the US Department of Energy Joint … Brad: Yeah, for sure. So we’re going back to the mid-late ’80s. And at that time, you know, it’s before genomics … Brad: It was a complex chemical. Yeah, for sure. And the NMR didn’t sort it out too quickly. But when we told them …

… DAN UDWARY: You’re listening to the Department of Energy … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … machine learning really would help distinguish and predict novel gene clusters. DAN UDWARY: Yeah, it certainly could. …

… JGI-led team significantly expands the global diversity of large and … capturing genomes of uncultivated giant viruses from environmental sequences across the globe, then using these … researchers previously applied this approach to uncover a novel group of giant viruses dubbed “Klosneuviruses.” …