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JGI@25: From Life at the Extremes to Editing Genomes
… system’s immense collection of publicly accessible metagenomic datasets from a wide variety of ecosystems around … of miniature CRISPR-associated proteins that can target single-stranded DNA. Such proteins have been adapted for … scoutRNA Is Required for Some Type V CRISPR-Cas Systems Mol Cell. 2020 Aug 6;79(3):416-424.e5. doi: …
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2024 Progress Report
… The Integrative Genomics Building (IGB) seen above is home to the DOE Joint … secondary users who made use of our data. We completed 39,870 projects in FY24 We generated 871 Terabases of … sequence We synthesized 9.7 Megabases of DNA We processed 13,700 metabolomics samples With our users, 247 publications …
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Tanja Woyke Elected to American Academy of Microbiology
… Laboratory (Berkeley Lab), Woyke has led JGI’s Microbial Genomics Program since 2009 and heads the Single Cells group. She has also served as the Functional Genomics …
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Tanja Woyke Awarded van Niel International Prize for Studies in Bacterial Systematics
… in, on and around the planet–through techniques including single-cell genomics and metagenomics. They cited her “landmark” 2013 Nature paper , …
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Making a Lichen Together
… the fungus and alga, either separately or together, on nitrocellulose filters in Petri dishes. The scientists also … in the lichen lifestyle. The team’s results appear in  BMC Genomics . To explore the genomes, Armaleo and colleagues … by a DOE-Biological Environmental Research grant No FWP 61327 to FRC and PL (for RNAseq). The work at the Joint Genome …
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Rex Malmstrom
… high throughput approach for isolating individual bacterial cells and amplifying their genetic material, thus bypassing … the Microscale Applications group to operate a similar single-cell genomics pipeline that provides JGI users access … His group also handles the Stable Isotope Probing (SIP) Metagenomics pipeline  that reveals in situ functional …
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JGI Scientists Pen Genome Watch Articles
… Laboratory, are sharing their expertise in environmental genomics by writing for the column Genome Watch in  Nature … “Given the great expertise in microbial genomics and metagenomics of the microbiology-focused groups at the Joint … characterizing the human microbiome  by its genomes and metagenome , rather than just by 16S ribosomal RNA gene …
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Thousands of small, novel genes predicted in global phage genomes
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Danielle Goudeau
… Danielle operates the single-cell genomics pipeline for JGI collaborators. This work combines …
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Access to Rock Star Scientists
… Through the JGI-UC Merced Genomics Internship, graduate students Candace Cole, Mo … UC Merced JGI Mentors : Tanja Woyke & Jessica Jarett, Single Cells Group “My experience at JGI has exposed me to the …
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DAP-seq Drives Robust Mapping of Gene Regulation
… allow simultaneous measurement of multiple samples in a single experiment — and integrated these data with single-cell gene expression maps. Together, the scale of data … have propelled the creation of a vast resource: nearly 3,000 genome-wide binding maps for 360 transcription factors …
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Mapping Heat Resistance in Yeasts
… its closest relative S. paradoxus at high temperatures (39°C/102°F). The Impact One of the challenges in … biofuel production. Efforts such as the 1000 Fungal Genomics Project led by the DOE Joint Genome Institute … to generate a huge pool of mutants, each containing only a single copy of a given gene rather than the two that are …
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