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A Natural Mechanism Can Turbocharge Viral Evolution
… Understanding how a fundamental mechanism of evolution allows microbes to adapt to changing … cell’s membrane. Two decades ago, a team discovered a group of viruses that had in their genomes a surprising tool: a … questions, a team led by scientists at the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office …
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Better Genome Editing for Bioenergy
… A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in … tool will make the right cut, researchers created a set of guide RNAs that were effective against 94 percent of the genes in a lipid-prolific yeast. The Impact The team … MB) and NSF  1706545 (IW). HA and JW were supported by the Office of Naval Research under grant  N00014-15-1-2785 . JW …
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Marine Microbe Contains Multitudes
… microbial genomics reveals one bacterial species is made of four ecologically distinct groups with different … to the blue-lit twilight zone, to the continuous pressure of the dark abyss, 4000 m (2.5 miles) deep. Scientists have … to different oceanic depths and relying on different ways of living. The Impact Microbes help regulate the global …
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First Monoploid Reference Sequence of Sugarcane
… . The Science Most species are diploids and have two sets of chromosomes, one from each parent. In contrast, many crops have multiple sets of chromosomes (they are “polyploid”) and their complex … to sequence and assemble, in turn limiting the use of modern, genomic breeding in these crops. For diploid …
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Gut Fungi: Unexpected Source of Novel Chemicals
… The Science Anaerobic fungi, which die in the presence of oxygen, dwell in herbivore guts and help them digest … meal. In their evolutionary history, these fungi branched off early from aerobic fungi, which can breathe oxygen — just like we do. Oxygen is a rich source of energy, and because anaerobic fungi can’t harness it, …
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Ben Bowen
… BS – University of Arkansas, Fayetteville, Chemical Engineering Ph. D. – … 2024 Berkeley Lab Recognition of Excellence Award 2016 R&D 100 Winner 2014 Berkeley Lab … T., Ruebel, O., Northen, T., & Bowen, B. (2015). Analysis of metabolomics datasets with high-performance computing and …
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JGI@25: From Life at the Extremes to Editing Genomes
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … nature was using it to do something important.” Related Publications:  A scoutRNA Is Required for Some Type V …
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Four Researchers Join JGI User Executive Committee
… have been elected to the User Executive Committee of the Joint Genome Institute, a Department of Energy user facility located at Lawrence Berkeley National Laboratory. Holly Bik of the University of Georgia, Greg Bonito of Michigan State …
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
… characteristics — creating many different ways of processing nitrogen. To boost crops more efficiently in … — they rely on enzymes that have been evolving for billions of years. However, these enzymes are often loosely understood, leaving potential targets for crop …
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Building Wet and Dry Lab Skills
… Summer 2025 marked the second year of Alabama A&M University students coming to the DOE Joint … experience funded by a DOE training grant.  Building off the previous year’s project, undergraduate interns … the Plant Functional Genomics Group to study the effects of  Brachypodium distachyon plant root exudates on the plant …
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JGI-UC Merced Interns Share Their 2021 Experiences
… During the summer of 2021, 13 interns from UC Merced spent eight weeks working … hone science presentation skills, and participate in professional development enrichment activities. For some … Merced internship program was founded in 2014 with the goal of inspiring students to embark on a career in genomics and …
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Charting Progress toward Professional Goals
… from their summer experiences at the JGI Berkeley Lab offers a variety of programs to help inspire and train the next generation of STEM professionals. Students can apply for internships …
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