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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… versatile engineering system that allows scientists to conduct genome-wide screens and explore biosynthetic pathway. … lands the cover of ACS Synthetic Biology. (Wayne Keefe/Berkeley Lab) For example, the JGI first used CRAGE to … of stable, synthetic microbial communities to take advantage of their joint metabolisms. Because, together, microbes …
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JGI Announces 2025 New Investigator Portfolio
… of projects, including the genomic dynamics of biofuel-producing fungi, the effects of biochar on rhizosphere … pathways of algae. They will harness JGI capabilities such as metatranscriptomics and environmental DNA sequencing …
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JGI Hosts GPU Hackathon in May
… of on simulation codes. “JGI is one of the largest producers of environmental genomics data and has a strong …
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A Community Resource for Secondary Metabolite Researchers
… by most living creatures for energy, growth and reproduction—most organisms produce a set of "secondary … (JGI), a DOE Office of Science User Facility located at Berkeley Laboratory, built off past experience in developing … and secondary metabolites information from isolate and metagenome data.   The SMC ( smc.jgi.doe.gov ) is designed …
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iPHoP: A Matchmaker for Phages and their Hosts
… these hosts are microbes like bacteria, not humans. With metagenomic sequencing, researchers have found more of these … matching these viral genetic sequences to their hosts is crucial to understanding what these viruses can do. Building … a DOE Office of Science User Facility at Lawrence Berkeley National Laboratory, aimed to streamline a process …
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Matt Blow
… training Wellcome Trust Sanger Institute, UK and Lawrence Berkeley National Lab … Bowers et al. 2024. scMicrobe PTA: … Editorial board member for Scientific Reports … Education … Selected Publications … Awards and Service …
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New Research Sheds Light on Diversity in the Deep Sea
… how life thrives in extreme environments. They also produce a range of novel enzymes and other biomolecules that … a DOE Office of Science User Facility at Lawrence Berkeley National Laboratory, contributed metagenomic sequencing to the study as well as  genome …
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Marchantia Pangenome Highlights Adaptive Nature of Plant Lineages
… a DOE Office of Science User Facility located at Lawrence Berkeley National Laboratory through the Community Science … to their environments, two gene families—peroxidases and nucleotide-binding leucine-rich repeats (NLRs) —stood out for their roles. …
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A Collaboration to Improve Plant Genome Annotations Across Species
… recently published work on the JGI Plant Gene Atlas in  Nucleic Acids Research . The project spans 15 years and … (JGI)*, a national user facility located at Lawrence Berkeley National Laboratory, and add additional gene … databases with large-scale transcriptome projects such as Expression Atlas and PPRD could help with …
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Identifying the Microbial Cleanup Crew at a Superfund Site
… up the toxic chemicals is commonly known as Enhanced Reductive Dechlorination (ERD.) It is dependent on the presence … a DOE Office of Science User Facility located at Lawrence Berkeley National Laboratory and used to identify the … Science Program , they were able to analyze the resulting metagenomic data. (Data from the project are available on the  …
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
Institutes of Health. The DOE works with the National Nuclear Security Administration to maintain the U.S. nuclear weapons stockpile and was interested in investigating … and resources focused on three human chromosomes: Lawrence Berkeley National Laboratory researchers were studying …
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New Research Finds Flagella in the Terrestrial Roots of Marine Bacteria
… help inform engineering microorganisms for biofuel production and other sustainable applications. Summary Hot … that enable organisms to swim around. However, genome and metagenomic sequencing conducted by the U.S. Department of … a DOE Office of Science User Facility at Lawrence Berkeley National Laboratory, has unveiled these motility …
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