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… By studying the structure and function of a cyanobacterial protein, researchers have new insights … cycle carbon in changing conditions. The products of photosynthesis are easy to point out. Plants, algae and … what is now the  Community Science Program Functional Genomics proposal call, the JGI synthesized hundreds of  …

… user engagement. The Science In addition to the core set of "primary metabolites"—chemical compounds shared by most … growth and reproduction—most organisms produce a set of "secondary metabolites," chemical compounds that often … more than 13 million BGCs in the catalog at the time of publication, it is the largest repository of BGC sequence …

… The Integrative Genomics Building (IGB) seen above is home to the DOE Joint … for a sustainable bioeconomy. Mission  As a U.S. Department of Energy Office of Science user facility, we provide advanced genomic … processed 13,700 metabolomics samples With our users, 247 publications were published   …

… analysis for synthetic biology and functional genomics. Prior to joining the JGI, he was a group lead at … National Laboratory where he focused on functional genomics of phototrophs. Through this and post-doctoral … B.Sc. (HONS) – University of Wales, Cardiff, Genetics Ph.D. – University of …

… Dr. Roux joined the JGI in 2017 to lead viral genomics research as part of the Metagenome Program. His responsibilities include the … of community-building efforts in the field of viral ecogenomics. For this role, Dr. Roux can rely on more than 10 … virus diversity and host interactions through global metagenomics. Nature 578, 432–436. …

… By characterizing the structure and function of a methylthio-alkane reductase system, researchers could … more.  Microbes excel at recycling the abundant miscellanea of their surroundings. Case in point: for us, the smell of the ocean simply signals we’re near the beach. For …

… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … with the HudsonAlpha Institute for Biotechnology.   Publications Grimwood, J., Gordon, L., Olsen, A. et al. The …

… A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in … tool will make the right cut, researchers created a set of guide RNAs that were effective against 94 percent of the genes in a lipid-prolific yeast. The Impact The team … MB) and NSF  1706545 (IW). HA and JW were supported by the Office of Naval Research under grant  N00014-15-1-2785 . JW …

… data set will help identify how different elements of the ecosystem interact and respond to changes in the … their genetic diversity. They hold economic value as both biofuel feedstock and their role in carbon sequestration. … managed through human intervention. By leveraging metagenomics, scientists were able to analyze the DNA of …

… After studying the mechanism of action of antifungal natural products and their … deciphered function and host-symbiont interplay using metagenomics. Taking on a Research Scientist position in 2007, she switched gears from metagenomics to single-cell genomics, which is now her primary …

… Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary … and the  DOE Systems Biology Knowledgebase (KBase) . Metagenomics is the study of the microbial communities in the … with a host – with 23,000 MAGs. Modeling A New Path for Metagenomics Researchers Building upon these resources, KBase, a …

… For the Joint Genome Institute, the end of 2018 was marked by a celebration of contributing over one “petabase” – a quadrillion … has begun to the June dedication event of the Integrative Genomics Building—the new home of the JGI and KBase in the …