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Boosting Small Molecule Production in Super “Soup”
… Program at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … first time CRISPR-Cas9 had been used to modify a cell’s  genome in order to create lysates with altered metabolic … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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Computationally Classifying Fungal Lifestyles
… Machine learning methods were applied on sequenced fungal genomes to classify gene families. The Science As a proof of … that “taught” a computer how to classify 101 representative genomes of Dothideomycetes, the largest class of fungi, by … to identify data generated in part through the 1000 Fungal Genomes Project, including 55 newly-sequenced species.  The …
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JGI@25: Mapping Switchgrass Traits with Common Gardens
… switchgrass is among the JGI Flagship Plants . Since 2007, the JGI has been working on identifying switchgrass genes … crop. In 2018, the JGI had sequenced and assembled the genomes of two varieties of a close relative and model … high-quality reference sequence of the complex switchgrass genome. The reference genome built off more than a decade of …
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A Sorghum Pangenome Opens More Doors to Discovery
… decades of technological development, dozens of reference genomes and thousands of resequenced sorghum varieties, a … traits that let this biomass powerhouse thrive. Within its genome, Sorghum bicolor holds keys to drought and flood … on sorghum has focused on producing high-quality reference genomes. By cataloguing a genome sequence for a line of …
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From Berkeley to Binghamton: Tracking Strawberry Evolution
… 2015, Adam Session was a postdoc working at the DOE Joint Genome Institute with Dan Rokhsar, who also holds a joint … known as polyploidy. The multiple copies arise from past genome duplication, which occurs in two basic ways. In “autopolyploids”, genome duplication occurs within a single species. By …
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Genome sequences of key bacterial symbionts of entomopathogenic nematodes: Xenorhabdus cabanillasii DSM17905, Xenorhabdus ehlersii DSM16337, Xenorhabdus japonica DSM16522, Xenorhabdus koppenhoeferii DSM18168, and Xenorhabdus mauleonii DSM17908
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JGI Workshop at SIMB NP Meeting
… Jan. 7: New Capabilities to Study Secondary Metabolism   Although … a given BGC in various hosts, availability of sequenced genomes, and computing resources needed to predict BGCs from available genome sequences. The DOE Joint Genome Institute (JGI), a …
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Enlarging Windows into Understanding Gene Functions
… four letters represents an organism’s genetic code, or genome, which underlies physical features and functions. … the structures and functions of the genes encoded in the genome sequence is part of the integrative science mission of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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Access to Rock Star Scientists
… JGI Mentors : Ben Cole & Axel Visel, Genomics of Plant-Microbial Interactions “The summer internship has further …     Mo Kaze, UC Merced JGI Mentor : Susannah Tringe, Microbial Systems Group “Everyone here is very kind and …
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… This is where the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … is famous for its work sequencing human and environmental genomes. But we now have these DNA synthesis capabilities … the enzyme-encoding constructs, the team studied more than 70 enzymes and how they grab hold of different substrates. …
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Crysten Blaby-Haas
… user capability between the JGI and Molecular Foundry for genome-encoded biomaterial discovery, design, and … and led the Quantitative Plant Science Initiative (2017-2022), a BER Science Focus Area (SFA).  … into the red algae and eukaryotic evolution from the genome of Porphyra umbilicalis (Bangiophyceae, Rhodophyta). …
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Polar Phytoplankton Need Zinc to Cope with the Cold
… researchers at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … Science Program (CSP) .  Through this collaboration, in 2017, they published the first genome sequence of a cold-adapted microalga: the diatom … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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