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Extracting the Secrets of Secondary Metabolites
… for survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and CRAGE technologies. While CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is the leading tool … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science User Facility, …
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Sequencing Sphagnum Leads to Discovery of Sex Chromosomes
… A nuanced understanding of peat moss drives insight into carbon storage   The Science Boggy peatlands, … these boggy wetlands produces an estimated 5% of annual greenhouse gas emissions. Understanding how sphagnum, a … (A.J.S.) conducted by the US Department of Energy (DOE) Joint Genome Institute ( https://ror.org/04xm1d337 ), a DOE …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… This single environmental trigger highlights efficiency for users requiring multiple omics methods to examine microbial chemical production. The Science Soil bacteria … This work conducted by the U.S. Department of Energy Joint Genome Institute (https://ror.org/04xm1d337), a DOE …
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New Research Sheds Light on Diversity in the Deep Sea
… Microbial communities living near hydrothermal deep-sea vents hold vast potential for …   The Science Hydrothermal vents are ocean-floor openings in the Earth’s crust that emit hot, mineral-rich water. … and DBI-2047598 to K.A. We thank the Department of Energy Joint Genome Institute (Community Science Program award 339, …
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An Automated Tool for Assessing Virus Data Quality
… fragments and data quality. The Science Through advances in sequencing technologies and computational approaches, more and more … and guidelines for providing the minimum amount of information for an uncultivated virus genome. CheckV has … The work conducted by the U.S. Department of Energy Joint Genome Institute is supported by the Office of Science …
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In Hot Spring Microbial Mat, Viruses Ride “Piggyback”
… a team has comprehensively described host-virus dynamics in a microbial mat. The Science In microbial mats, communities of microorganisms live among … virus in 34 hosts or 26 percent of the single cells. Metagenomics sequencing then allowed the team to ask, for the 34 …
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Gene Expression: From On-Off Switch to Dial
… Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science Scientists have developed a more nuanced library approach to tuning gene expression in metabolic pathways. Compared to the … Foundation, and the JGI Synthesis Program under FP00005685. In addition, M.D. acknowledges funding from a National …
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iPHoP: A Matchmaker for Phages and their Hosts
…   To understand virus-host dynamics, computation helps fill in what cultivation can’t. The Science At first, viruses are merely toolkits. To do anything, they must find a host, and not just any host will do. … will strengthen future virus-host predictions. This information could open the door to improving crop yields and a …
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The Case for Conservation
… How sex chromosomes “older than dinosaurs” could help improve crop yields.  The Science The … sequences of the male and female plants, each representing a single set of chromosomes, are available. The genome … start-up funds from UF to S.F.M.; microMORPH Cross-Disciplinary Training Grant, Sigma-Xi Grant-In-Aid of Research, and …
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Cataloging the Microbes that Manage the Health of River Systems
… Database provides details on river microbes in 90% of US continental watersheds. The Science In a recent … States. They also provided multiple access points to the information. The team harnessed a community-science program to … available, river-focused microbial resource that provides information at multiple scales from genes to the community …
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The Surprising Structure of a Shrub Willow Sex Chromosome
… the sex chromosomes of mammals is, for the first time, seen in a plant. The Science Sex in plants can be befuddling. Most species are hermaphrodites, expressing both male … provided by the National Natural Science Foundation of China (31590821, 31561123001, 31500502, 41871044), National …
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From Stress to Growth: The adaptive mechanisms of algae in changing Arctic waters
… P. psychrophila genes drive resilience when salinity fluctuates. The Science The Arctic microalga Plocamiomonas psychrophila can thrive in changing conditions. A recent study shows that when salinity is … The study was funded by Natural Sciences and Engineering Research Council of Canada (NSERC) Discovery …
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