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Supercomputing, MetaHipMer and the Mega Dataset of Lake Mendota
… Sequencing technology has changed dramatically over the last  25-plus years since the JGI’s inception, making it possible for researchers to get a close … Berkeley National Laboratory, is committed to advancing genomics in support of DOE missions related to clean energy …
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A Sorghum Pangenome Opens More Doors to Discovery
… Leveraging decades of technological development, dozens of … the traits that let this biomass powerhouse thrive. Within its genome, Sorghum bicolor holds keys to drought and … flood resilience, biomass production for fuels, and growth in poor soils. In addition to bolstering sorghum fields, …
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Extracting the Secrets of Secondary Metabolites
… for survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and CRAGE technologies. … or activate certain genes and assess how these edits affect functionality.  CRAGE allows for the transplanting of these …
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JGI@25: Tracking & Subduing the Plague of California’s Oak Woodlands
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements … will help solve energy and environmental challenges.   Scanning the California oak woodlands from the air, large swaths … al. Phytophthora genome sequences uncover evolutionary origins and mechanisms of pathogenesis . Science. 2006 Sep …
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A Community Resource for Secondary Metabolite Researchers
… Collaboratory encourages user engagement. The Science In addition to the core set of "primary metabolites"—chemical compounds shared by most living creatures for energy, growth and reproduction—most … known as biosynthetic gene clusters (BGCs.) As reported in the recent Database issue of the journal Nucleic Acids …
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Sequencing Sphagnum Leads to Discovery of Sex Chromosomes
… A nuanced understanding of peat moss drives insight into carbon storage   The Science Boggy peatlands, which … (A.J.S.) conducted by the US Department of Energy (DOE) Joint Genome Institute ( https://ror.org/04xm1d337 ), a DOE Office of …
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An Addiction Crucial to a Fungus’ Reproduction
… bacteria to regulate key components of its reproductive machinery The Science To better understand how beneficial … are transmitted between host generations, researchers investigated the role that bacteria living within a host (endosymbionts) have on fungal host …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… This single environmental trigger highlights efficiency for users requiring multiple omics methods to examine microbial chemical production. The Science Soil bacteria … This work conducted by the U.S. Department of Energy Joint Genome Institute (https://ror.org/04xm1d337), a DOE …
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New Research Sheds Light on Diversity in the Deep Sea
… Microbial communities living near hydrothermal deep-sea vents hold vast potential for …   The Science Hydrothermal vents are ocean-floor openings in the Earth’s crust that emit hot, mineral-rich water. … and DBI-2047598 to K.A. We thank the Department of Energy Joint Genome Institute (Community Science Program award 339, …
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In Hot Spring Microbial Mat, Viruses Ride “Piggyback”
… a team has comprehensively described host-virus dynamics in a microbial mat. The Science In microbial mats, communities of microorganisms live among … virus in 34 hosts or 26 percent of the single cells. Metagenomics sequencing then allowed the team to ask, for the 34 …
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Supercharging SIP in the Fungal Hyphosphere
… High-throughput stable isotope probing helps ID novel interactions between bacteria and fungi The Science … automated aspects of a commonly-used process for studying microbial communities, with results published in the  … The work conducted by the U.S. Department of Energy Joint Genome Institute ( https://ror.org/04xm1d337 ), a DOE …
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Fungal Friends or Foes in Plant Roots
… Uncovering associations between plant roots and fungi that can help … analysis identified fungal gene families that help determine if these fungi act as friends or foes. The Impact … communities comprised of fungi and bacteria can thrive in plant roots. They play key roles in maintaining the …
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