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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… chemical factories. They hold genetic blueprints for dozens of complex compounds, but stay largely dormant under … Researchers with the Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user … that precisely maps where transcription begins on the genome. This revealed a sweeping cellular response: The …
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Gut Fungi: Unexpected Source of Novel Chemicals
… The Science Anaerobic fungi, which die in the presence of oxygen, dwell in herbivore guts and help them digest their last leafy meal. In their evolutionary history, these fungi branched off early from … called natural products . Yet, combing through the genomes of four anaerobic fungal species has revealed, for …
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The Surprising Structure of a Shrub Willow Sex Chromosome
… A genetic architecture that is characteristic of the sex chromosomes of mammals is, for the first time, … some, including shrub willow  Salix purpurea , employ the evolutionary strategy we are far more familiar with: … Laboratory and the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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Characterizing Communities: JGI Announces Latest CSP Portfolio
… Proposals aim to sequence and annotate genomes from Antarctica to Africa to global oceans. Through the Community Science Program of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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Soil virus offers insight into maintaining microorganisms
… The work was enabled in part by a community data portal of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … were retrieved using the  JGI’s Integrated Microbial Genomes & Microbiomes (IMG/M) data portal. The IMG suite is …
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Streamlining Regulon Identification in Bacteria
… with their target genes. The Science Regulons are a group of genes that can be turned on or off by the same regulatory … in Streptomyces coelicolor . The Impact As an integrative genome science user facility, connecting genes to functions … of the mission of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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JGI@25: Cow Rumen and the Early Days of Metagenomics
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … coherent pieces called contigs — into genes and even into genomes — from these environmental samples,” said Matthias … how JGI data supports higher education in this JGIota , a Genome Insider podcast minisode.)  “The ultimate target has …
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Expanding Horizons with the 2025 JGI-UC Merced Internship Cohort
… Interns contributed to a number of projects, from refining lab protocols at the bench to … has closed at the U.S. Department of Energy (DOE) Joint Genome Institute, a DOE Office of Science User … Asaf Salamov, Igor Grigoriev Project:  Training new JGI genomes with Tiberius Brandon Imstepf Mentor: Brian Bushnell …
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Training the Next Generation of Talent
… DOE JGI, UC Merced Days after presenting the results of his summer research at the U.S. Department of Energy Joint Genome Institute (DOE JGI), a DOE Office of Science user … I’ll take that knowledge back with me.” Now a second-year evolutionary biology student in David Ardell’s lab, he also …
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JGI Announces 2023 Community Science Program Awardees
… Congratulations to the proposers of the 19 proposals selected for the 2023 Community Science Program call of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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Fungus Fuels Tree Growth
… start pinning down how a fungal symbiont spurs growth of poplar, a potential biofuel feedstock.     The Science … partnered with the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … Program in order to get  M. elongata and  I. europaea  genomes sequenced and annotated for this study. The team …
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Simon Roux Named 2025 ASM Microbiome Data Prize Awardee
… Congratulations to US Department of Energy (DOE) Joint Genome Institute (JGI) staff scientist … Roux leads the Viral Genomics group within the JGI Metagenome Program, and coordinates the development of the virus …
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