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A Cost-Efficient Way to Convert Yeast into a Cell Factory for Hydroxyapatite
… hydroxyapatite, a high-value biomaterial with a wide range of industrial applications. The team was led by researchers at two U.S. Department of Energy national user facilities – the DOE Joint Genome … in the development and biotechnology applications of various biomaterials. These efforts align with BER …
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DAP-seq Drives Robust Mapping of Gene Regulation
… Multi-species assays yield an unprecedented view of plant evolution and adaptation.    Understanding how … complex wiring behind a city’s power grid. Just as the flow of electricity controls when and where lights turn on or … processes.  Traditionally, mapping this intricate network of regulatory “switches” in plants at a large scale was akin …
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Picking Up Threads of Cotton Genomics
… growing on plants, with fluffy white bolls bursting out of the green pods in every direction. There are 100 million … on cotton production, and the crop’s annual economic impact of $500 billion worldwide underscores its value and importance in the fabric of our lives. In the United States, cotton production …
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Shattering Expectations: Novel Seed Dispersal Gene Found in Green Millet
… Survey of Setaria's natural diversity reveals seed dispersal in … Center (Danforth Center) drove up and down the highways of the continental United States, occasionally pulling over to the side of the road to collect small weedy plants and bring them … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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An Enzyme System to Help Catalyze Bioproduction of Plastic
… By characterizing the structure and function of a methylthio-alkane reductase system, researchers could … more.  Microbes excel at recycling the abundant miscellanea of their surroundings. Case in point: for us, the smell of the ocean simply signals we’re near the beach. For …
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Defining a Pan-Genome for Antarctic Archaea
… Analysis of haloarchaeal metagenomes broadens understanding of Antarctic biogeography. The Science Haloarchaea flourish … primary replicon (chromosome) that is highly conserved and secondary replicons that are highly variable but organized … (project 4031). The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …
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An Automated Tool for Assessing Virus Data Quality
… (metagenomes). However, the quality and completeness of metagenome-assembled virus sequences vary widely. In a … to help researchers assess and improve the quality of metagenome-assembled viral genomes . The Impact The … step, numerous genes for antibiotic resistance and secondary metabolism would have been incorrectly attributed …
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Fields of Breeders’ Dreams: A Team Effort Toward Targeted Crop Improvements
… crop and ornamental seeds sold for the upper Midwest are often very different than those bred for Texas. Identifying … varieties that have high productivity across a range of environments is becoming increasingly important for food, … natural diversity in multiple locations, and then you are extracting links between the genetic variation and …
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Supercomputing, MetaHipMer and the Mega Dataset of Lake Mendota
… before. In 2006, the JGI produced 33 billion base pairs of sequence; by 2023, that number was almost 717 trillion. Last year, the JGI surpassed three Petabases of data sequenced — that’s three-quadrillion base pairs of … JGI users — both primary, data-generating users, as well as secondary, data-downloading users — have access to …
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Party in the Rhizosphere
… rhizosphere. In this episode, biologist Jennifer Pett-Ridge of Lawrence Livermore National Laboratory has your backstage …
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2024 Progress Report
… for a sustainable bioeconomy. Mission  As a U.S. Department of Energy Office of Science user facility, we provide advanced genomic … A record number of primary users — 2,475 — had active proposals with us, along with more than 15,000 secondary users who made use of our data. We completed …
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Effects of Polar Light Cycle on Microbial Food Web
… Populations of Antarctic lake microbial communities change with the … with light availability. A long-running time-series study offers a first glimpse into a full season’s cycle of this polar environment. This cycle suggests a reliance on … (project 4031). The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …
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