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A Community Resource for Secondary Metabolite Researchers
… user engagement. The Science In addition to the core set of "primary metabolites"—chemical compounds shared by most … growth and reproduction—most organisms produce a set of "secondary metabolites," chemical compounds that often confer specialized capabilities that allow the …
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Sequencing Sphagnum Leads to Discovery of Sex Chromosomes
A nuanced understanding of peat moss drives insight into carbon storage   The Science Boggy peatlands, which hold much of the Earth’s carbon as well as material that can be converted to energy, are made up heavily of sphagnum mosses.  New research identifies sex chromosomes …
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An Automated Tool for Assessing Virus Data Quality
… (metagenomes). However, the quality and completeness of metagenome-assembled virus sequences vary widely. In a … to help researchers assess and improve the quality of metagenome-assembled viral genomes . The Impact The … DNA sequencing can help scientist to recover the genomes of these viruses and associate them with their microbial …
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How Filamentous Fungi Sense Food
… . The Science A team led by researchers at the University of California, Berkeley used a multi-omics approach to … N. crassa is the model organism for filamentous fungi, all of which contain a wide array of plant cell-wall degrading enzymes (PCWDEs) that allow …
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In Hot Spring Microbial Mat, Viruses Ride “Piggyback”
… a microbial mat. The Science In microbial mats, communities of microorganisms live among viruses that infect them. But … a more systematic picture through single-cell and metagenomic sequencing. A team co-led by Mária Džunková, … virus in 34 hosts or 26 percent of the single cells. Metagenomics sequencing then allowed the team to ask, for the 34 …
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Understanding Wildfire Recovery, Starting in Soil
A metagenomic look at the soil microbes present a year after a … begins at the forest floor. Within the soil, a microbiome of bacteria, viruses and fungi process carbon and nitrogen, … helped fungi, bacteria and viruses survive. With this metagenomic analysis, it was possible to identify specific …
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Supercharging SIP in the Fungal Hyphosphere
The Science Researchers have successfully automated aspects of a commonly-used process for studying microbial … with results published in the  November 2022 issue of Microbiome . High-throughput stable isotope probing (SIP) … and improve results. Applying this method to the study of a particular fungi, researchers identified novel …
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Gene Expression: From On-Off Switch to Dial
… to expression, scientists can now opt for various shades of grey. The ability to fine-tune the level of gene expression allowed researchers to identify variations of essential genes in metabolic networks that were missed …
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The Case for Conservation
… genome . Now, high-quality reference genome sequences of the male and female plants, each representing a single set of chromosomes, are available. The genome assemblies … continents, including Antarctica where it is a major part of the flora, fire moss has adapted to conditions such as UV …
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iPHoP: A Matchmaker for Phages and their Hosts
… hosts are microbes like bacteria, not humans. With metagenomic sequencing, researchers have found more of these viruses than ever before, in all kinds of … as terrestrial soil, having additional isolates and metagenomic datasets will strengthen future virus-host …
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Cataloging the Microbes that Manage the Health of River Systems
Database provides details on river microbes in 90% of US continental watersheds. The Science In a recent Nature … also funded under the RC-SFA at PNNL by DOE BER ESS. Metagenomic and metatranscriptomic sequencing was performed at … Science Program and the University of Colorado Anschutz’s Genomics Shared Resource. The work (proposal …
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Identifying the Microbial Cleanup Crew at a Superfund Site
PCE (perchloroethylene) found its way into the groundwater of several communities in New Mexico via leakage from a … bioremediate toxic substances has led to the development of cost-effective environmental cleanup strategies. Summary … Program , they were able to analyze the resulting metagenomic data. (Data from the project are available on the  …
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