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JGI announces 2024 Functional Genomics awardees
… year, the JGI accepts proposals for state-of-the-art functional genomics research from reseachers who translate genomic … Through our CSP Functional Genomics call , we look for projects that will leverage the JGI’s DNA synthesis and omics capabilities to enhance understanding of gene and genome function. Tapping into these functions allows …
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A Redesign for Yeast’s Genome, Chromosome by Chromosome
… To engineer yeast to do more, and understand genomes in general, Jef Boeke, Weimin Zhang (NYU Langone Health) and Leslie Mitchell (Neochromosome) have worked … yeast’s native chromosomes with synthetic versions. This project has turned out to be an international collaboration, …
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JGI announces 2025 Functional Genomics awardees
… Olufemi Isimikalu, Todd H. Oakley, BJ Philmus and Aaron M. Roshotte; [Below] Paul Scesa, Kathleen Scott, Tiffany … Through our  CSP Functional Genomics call , we look for projects that will leverage the JGI's DNA synthesis and omics capabilities to enhance understanding of gene and genome function. Tapping into these functions allows …
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Better Genome Editing for Bioenergy
… technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a powerful, high-throughput … at a genetic level, how does  Y. lipolytica work? The project was a multi-institutional effort led by … included researchers at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User …
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A Grass Model to Help Improve Giant Miscanthus
… of polyploidy and perenniality. The Science A reference genome sequence and genomic toolkit for the perennial grass … chromosomes of Miscanthus arose by ancient hybridization (polyploidy) and insights into the dynamics of gene … Europe and Asia. CABBI partners include the University of California, Berkeley and the HudsonAlpha Center for …
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Ray Turner Completes Last Tour of Lab Duty at JGI
… For the last 15 years, Ray Turner has been one constant for the Joint Genome Institute. On July 1, 2020, that all changed. Ray’s … at a high level as JGI transitioned from the Human Genome Project to gaining momentum as a national user facility. He … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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A Natural Mechanism Can Turbocharge Viral Evolution
… Understanding how a fundamental mechanism of evolution allows microbes to adapt to changing environments. The … ago, a team discovered a group of viruses that had in their genomes a surprising tool: a “diversity generating … as genomes sampled all at once from the same environment, called metagenomes. Why? Simon Roux, who led the research …
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You Can Move, But You Can’t Hide
… and spread from cell to cell. Two of the most common forms of MGEs are viruses and plasmids. They can be found … software tool  recently described in  Nature Biotechnology  called geNomad identifies and classifies MGEs based upon … Lead Nikos Kyrpides at the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility at …
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Jeremy Schmutz
… back to 1997, when he was working for the Stanford Human Genome Center, now the HudsonAlpha Institute for Biotechnology. There he constructed … 5, 16, and 19. Following the completion of the Human Genome Project in 2003, he developed sequencing, assembly, and …
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Promoting the Power of Viral Metagenomics
… of viral metagenomics, authored by JGI researchers Lee Call,  Stephen Nayfach and  Nikos Kyrpides , was  recently … early 2020, people all over the world have been forced to confront the awesome power that viruses have to affect nearly every aspect of our daily lives.  But for researchers who study viruses that …
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Supercomputing, MetaHipMer and the Mega Dataset of Lake Mendota
… over the last  25-plus years since the JGI’s inception, making it possible for researchers to get a close look … For example, with support from the  Exascale Computing Project , the JGI — along with the National Energy Research … to enable large-scale analysis. The story of a massive metagenome assembly for a time-series experiment from the …
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Training the Next Generation of Talent
… his summer research at the U.S. Department of Energy Joint Genome Institute (DOE JGI), a DOE Office of Science user facility, Keedrian Olmstead was back on campus at the University of California, Merced to start … challenges UC Merced graduate students with individual projects at the DOE JGI that provide hands-on experience in …
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