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Apple Podcasts or wherever you’re getting this and tell me why you’re listening. DAN: But, now, here’s Natural Prodcast … of, actually. DAN:  Absolutely. How do you get started on building a collaborative community like that to do such a … And that’s been followed by developments in pulse sequences and improvements in the ways in which you acquire …

… pipelines.  You will receive automated emails as raw sequence data becomes available, and as analysis is …

As waters warm due to climate change, corals are in mortal peril. But corals comprise multiple organisms: a coral host, a … a little-characterized microbiome. When warm waters stress corals, it might be their microbes, including their …

… enzymes are, right? ALISON NARAYAN: Yes, and so that’s why I don’t like that sentence. I think that sometimes, we … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh … element that needs to be taken into consideration in building these models. And so I think that one of the …

… there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … protein or the genes that you are analyzing. And then we’re building phylogenies a lot, making phylogenetic trees, and … it would work, but we actually found fosmids. And we sequenced the whole fosmid at the time with Sanger …

… least, talk to us, first about my definitions of things and why I am wrong, and also talk about some of the great … think the terms we should be using for what we do are, and why there and why it’s important to make those distinctions. … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the …

… at genomes and seeing where the really hard things to sequence were, and wondering what those … what those were … functional was these secondary metabolite pathways. So why was that? What is it about secondary metabolite pathways … really interesting – when you can begin to see these guys building better weapons against one another. That gives us …

… more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … the pieces that attached to the other pieces, and sort of building out the puzzle from there to find that vein of … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene …

DAN: Alright, so I think we’ve covered a little bit about why they’re important. But one of the things I did want to … live in the root nodules of plants. And these guys were sequenced, and you can see that different Frankia have … metabolites. And they often use primary metabolites as building blocks to produce novel molecules. And so we’ve got …

… in the analysis and publication of the claimed genome sequences. This opportunity, provided by the Department of … builds upon thousands of microbial genomes that have been sequenced by the JGI though not formally analyzed or … biological inference. … Genome sequences of key bacterial symbionts of entomopathogenic nematodes: Xenorhabdus …

… all those art history photos of the, you know, various old buildings in in Rome didn’t quite do it for me. And at the … then genomics happened. Dan: Yeah, I did my first genome sequence with you. Brad: That’s right,  Dan: JGI did it in … working with you, Dan, on this one, and we said, “Well, why don’t we have you know, the bioinformaticians go against …