Search

… more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene … from certain kinds of environments or certain kinds of species or whatever. So for example, if you wanted to go …

… about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean … family would be a set of gene clusters across different species, which all encode the production of either the same …

… in the project by watching Amanda Hurley’s presentation from the 2019 JGI Genomics of Energy & Environment Meeting.] … at genomes and seeing where the really hard things to sequence were, and wondering what those … what those were … functional was these secondary metabolite pathways. So why was that? What is it about secondary metabolite pathways …

… is a bacterial sacred metabolite, and ergot alkaloids come from fungi, and Taxol from plants. Plants, fungi, bacteria, … DAN: Alright, so I think we’ve covered a little bit about why they’re important. But one of the things I did want to … live in the root nodules of plants. And these guys were sequenced, and you can see that different Frankia have …

… least, talk to us, first about my definitions of things and why I am wrong, and also talk about some of the great … They produce a large array of different molecular species related– chemically related– but nevertheless we did … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the …

… our interview this week is with Professor Brian Bachmann from Vanderbilt University’s Chemistry Department, where he … And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, …

… of phage and virus genomes have been assembled and reported from metagenomes, our understanding of the impacts of these … to identify, filter, cluster, annotate, and bin viruses from metagenomes. mSystems 9:e00888-24. … Collect CRISPR spacers from metagenomic reads at scale …

… QC Protocol DNA Extraction 101 : tips, kits, and protocols (from PacBio) Guidance for sample collection and storage (from PacBio) Best practices for High Molecular Weight DNA extraction and quality control (from PacBio) 2) Review guidelines detailing quantity and …

… Laboratory. Being a User Facility means that scientists from all over the world bring us big problems related to … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … at MIT, and I studied microbial ecology. I studied Vibrio species in the ocean, so heterotrophic bacteria. Now, we …

… in the analysis and publication of the claimed genome sequences. This opportunity, provided by the Joint Genome … builds upon thousands of microbial genomes that have been sequenced by the JGI though not formally analyzed or … talent for biosciences.  Adopt-a-Genome has: ~20 faculty from institutions across the country Efforts in ongoing …

… we have our conversation with Professor Alison Narayan, from the University of Michigan. I hope she’ll accept this … enzymes are, right? ALISON NARAYAN: Yes, and so that’s why I don’t like that sentence. I think that sometimes, we … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh …