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Plant Microbial Interactions Group
… are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and … and are influenced by microbial partners. We use a variety of genomics-powered tools to study this complexity, … fungi, viruses. Resident viruses can be found in a myriad of bacterial strains, whereby they can modulate host …
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New Lineages of Life Group
… research is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, … metatranscriptomics, single cell genomics and phylogenomics) and machine learning to identify new …
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Single Cell Research Group
… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of interest. One such effort is … cells that are from candidate phyla, major branches in the phylogenetic tree without cultivated representatives. The …
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Industry Engagement Program
… joined the JGI in 2017, he brought with him 20 years of industry experience — and an opportunity to expand the JGI’s portfolio of user companies. Now the Department of Energy is uniting … technologies and state-of-the-art sample processing.  Our DNA synthesis platform enables users to test hypotheses via …
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FICUS
… for researchers to request the capabilities and expertise of multiple DOE National User Facilities in one research … provides customized analysis, the JGI also participates in publication of results. … for the annual FICUS call with EMSL begin with a Letter of Intent (LOI) from a researcher, briefly describing the …
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Protocols
… provided by JGI and the JGI user community below for DNA preparation tools, high molecular-weight DNA extraction and RNA preparation.  JGI sample QC protocols can be found here . DNA Extraction Protocols: … Tips for High Molecular Weight DNA extraction: …
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Natural Prodcast Episode 11: Marnix Medema
… Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … student in my group, Satria [Kautsar] built a really nice visualization tool around it, so you would actually be able … into 100, for example, sub domains”, where he made a big phylogeny of all the proteins that had the protein domain. …
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Natural Prodcast Episode 10: A Primer on Genome Mining
… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … amino acid out of solution and stick another amino acid or multiple other amino acids onto it to create a small …
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Secondary Metabolites Program
… Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … advantages to the organisms producing them, and are often involved in defense, nutrient acquisition and … their potential applications in the bioeconomy including biofuels, biochemicals and sustainable agriculture. …
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Metagenome Program
… uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … drive innovations that could advance our understanding of Earth’s ecosystems. … The Program focuses on developing computational tools and visualization resources that support user analysis of …
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Synthesis
…   The Joint Genome Institute's DNA Synthesis Platform capabilities support researchers exploring how to convert sequence into functional assessments. This is done by … automations for DNA design, assembly and analysis Overview of synthesis products The JGI DNA Synthesis platform enables …
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Natural Prodcast Episode 23: Aaron Puri
… DAN: Hey, everybody. Welcome back for another episode of Natural Prodcast. Right now I’m working on this the … of their synthases so that we can start to use the DNA sequence to predict or just understand better the … And one would envision that microorganisms have evolved multiple variations of these compounds. And so if you’re …
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