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MARCY: Sure. So my lab has really converged on the study of host-microbe chemistry. And the interactions– As much as we … talked to people who as part of a program studying Amazon ecology, [in] Portuguese, and got to do an independent study … And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much …

The Facilities Integrating Collaborations for User Science … provides customized analysis, the JGI also participates in publication of results. … Proposals for the annual FICUS … in rank order by the reviewers. The ranked proposal list, along with a recommendation from management at the JGI and …

With collaborative user projects, the JGI’s Plant Program delves into … by exploring plants’ role in capturing carbon, detoxifying soils, interacting with other organisms, and adapting to … the ability to discover syntenic orthologs, generate publication quality graphics and explore pangenome views of …

… of background. My name is Dan Udwary. I – as well as my co-host, Alison Takemura, whose voice you’ll hear in a minute – … I did a PhD in microbiology at MIT, and I studied microbial ecology. I studied Vibrio species in the ocean, so … is a chemical compound called geosmin that’s produced by soil bacteria that live all over the place. So that smell of …

… and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … disparate environments. There’s some marine. There’s some soil samples. There’s human gut samples. There’s lots and … metabolism genes don’t look like the genes in their host. And so, sometimes those kinds of things get lost in …

… the producing organism and strong interactions and the host or even in tripartite systems. So, in those cases, it’s … as a raw material telling us, hey something is happening along this particular route. There is expansions. You should … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

… and culture-disconnected. Like we’ll take some soil samples and sequence all the bugs out of that or … I think on COVID that we’re getting ready to submit for publication and have found some interesting hits for that as … naturalprodcast.com . Special thanks, as always, to my co-host Alison Takemura. If you like Alison, you want to hear …

… products because they’re easy to find. They grow in the soil. These are the same guys that produce geosmin. And so … know, like an organism. They have specialized cells and the ecology there is really fascinating, probably a bit under … at naturalprodcast.com Special thanks, as always, to my co-host, Alison Takemura. <woohoo> If you like Alison, and want …

… single cell work we’re doing. And using these together along with all of our computational tools to really build … being used to essentially domesticate a range of different host organisms through introducing “landing pads” that you … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …

… even know of your existence back then. So there was no hostilities. Dan Udwary: That is certain, yes. So welcome. I … a group of Jos Raaijmakers at the Netherlands Institute of Ecology and Victor Carrion who was the postdoc leading that … the action of the microbiome because if you sterilize the soil, the protective effect is gone. You can transplant the …

Every approved proposal starts with a User Agreement — before any … rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is … a version of the User Agreement between HHMI, your Host Institution and LBNL is required. NOTE:  If a PI …

… to join me in mentally welcoming Natural Prodcast’s new co-host, another old friend of mine, Professor Jaclyn Winter , … off through these areas. And you can do– with a teaspoon of soil from outside, you maybe have to do a 10,000-fold … goal of this research then? Is it to understand that ecology? Or are you still doing drug discovery BRIAN …