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… “Adopt a Genome” is an informal program for faculty to “claim” the JGI’s unpublished … faculty will work with undergraduates in the analysis and publication of the claimed genome sequences. This … A primary purpose of this project is to bring educators from a broad range of disciplines up-to-speed …

… The mission of the Joint Genome Institute is to serve the scientific community as … scientific discovery at the DOE Office of Science through high performance computing (HPC) and data analysis.  The DOE Systems … The researcher then submits a proposal for consideration in the next review cycle. All proposals undergo technical …

… challenge is, as the listeners know, even when you find a highly potent active compound that has a good cytotoxicity … I think on COVID that we’re getting ready to submit for publication and have found some interesting hits for that as … screen, I think having assays that are amenable to – high-throughput testing is really important for us. In this …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … so secondary metabolism is throughout nature, except maybe for animals and humans, not as much. You know, we have this … blocks to produce novel molecules. And so we’ve got glycosides being made into sugar-containing compounds, and …

… DAN: Welcome back for episode 9 of Natural Prodcast. This week, Alison and I talk to Roger Linington, from Simon Fraser University in British Columbia, … and so the quality – the data quality – was reasonably high. And yeah, it gave it gave us enough enough pairs of …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … two sequenced genomes of a Streptomyces , or gram-positive high GC organism.  Dan: Yeah, not a lot of natural product … on by putting the genes into a bacteria and doing in vitro work, and could make a toxin. And that was pretty cool …

… Our research is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning …

… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … but in subtle ways that affect fitness. And so, doing a high level kind of analysis, you just might not be able to …

… and microbiology just followed me all the way through my high school days in England.  DAN: What did your dad do in … and new ways to recover spinosyns. And so we had a high throughput screening platform where we’d look at 10,000, … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …

… mining and the directions it might take in the future. I highly recommend it. I’ll link to it in the show notes. … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all … is not on the data side, but it’s still really the high throughput of getting these clusters activated. So most of …

… DAN: Hey, everybody. Welcome back for another episode of Natural Prodcast. Right now I’m working on this the afternoon of the day I’m due to release it, … we’ll say methyl so we call them methylotrophs [ muh-thigh-luh-trophs ]. This is like, every square is a …