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… and scientists of secondary metabolism. Welcome back for our second season of Natural Prodcast. This first … I got the chance to do genome mining on more than 50,000 genomes that we derived from meta-genome sequences. As … what genome mining is, if I want to explain that to someone who doesn’t know much about genetics or anything else, …

… of the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it includes … quantity and quality has been the rate-limiting step for many projects at the JGI. The quality of the starting material is one of the greatest predictors of a successful sequencing …

… DAN: Welcome back for episode 9 of Natural Prodcast. This week, Alison and I … of biodiversity, of which natural products chemistry is one. DAN: So, I’ve always known Roger as an expert in … effort, and I want to say thank you, personally, to everyone involved in making this happen. We had a really fun …

… Mexico, and an incredibly bright guy who’s been thinking for a long time about the evolution and natural products … grow and have different perspectives– from the chemists on one side, microbiologists, and evolutionary biologists more … not all, of the pathways that people have been cloning and analyzing are producing not only one metabolite. They …

… Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … diversity and metabolic potential, with implications for energy production, environmental sustainability, and … such as carbon cycling, nutrient cycling, and energy flow. One of the key goals of the Program is to develop a deeper …

… and AI-driven analyses that convert biological information into actionable insights and solutions. … conversion efficiency, and discover microbial pathways for producing biofuels, biochemicals, and other high-value … reveal biological routes to recover, reuse, and transform critical minerals. This knowledge supports developing …

… help with: preparing a Statement of Work, completing a formal User Agreement, and ultimately launching the user’s project. See below for details on each step. … Before work can start on any approved proposal – including the submission of samples for sequencing, or the submission of sequencing data for …

… suggest you go back and check the first episode out. This one continues the introductory conversation between myself … so secondary metabolism is throughout nature, except maybe for animals and humans, not as much. You know, we have this … are more motile and move around and don’t sort of “set up shop” in one place. And so those those guys that move around …

… It’s been a while, but Natural Prodcast is back again for another round of episodes. If you stick around for the … to explaining what a CSP is, how you apply for and get one, and what happens once you do. Before we start, I … genomes, all our eukaryotic genomes. Fungal plant, algal genomes, a lot of effort goes into generating these …

… genome miners use, including antiSMASH, MIBiG, and newer efforts, like BiG-scape and BiG-SLiCE, and now the BiG-FAM … Crashing. Maybe it’s what I’m used to thinking of, like someone crashing at someone else’s place. OK. That helps me. Dan … effort. Then we can do something together. Dan Udwary: So stop planning and just do it. Marnix Medema: Yeah, well it …

… “Adopt a Genome” is an informal program for faculty to “claim” the JGI’s unpublished microbial genomes, with the expectation that faculty will work with … insights from sequence data, employing IMG data and tools for comparative analysis, visualization and interpretation …

… to Natural Prodcast! This is episode 4! From here on out, for a while, we’re going to be presenting some conversations … which seem to be history.   I should mention that this is one of several interviews you’ll hear which we recorded at … is that? It looks like it’s encoding an enzyme, there’s no stop. So finding out – expressing the quiet clusters and …