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… try to understand the biosynthetic pathway or to help identify the compound that they were interested in. But nowadays, … on the backs of people who’ve done a lot of work over the years. We have a pretty good idea of what the different … is another community effort that’s been built up over the years and is really strong for finding lots of different …

… can we utilize sequences of these TetRs to identify what molecule might bind them and then allow for their … so that's a new JGI project. Just came out from a CSP this year. BETSY PARKINSON: Yes. DAN: So how long do you expect … But what was really interesting is when I started my lab in 2018, several papers came out right in a row all about this …

… as a new type of medicine that will open up a new year for targeted anti cancer drug discovery. DAN: Yeah, … drug conjugates, abbreviated as “ADC”, was approved in the year 2000, and utilize the enediyne as the payload. We call … if you are a microbiologist in the 40s, how do you classify a strain? You look at it and this is the 40s – you don’t …

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… advisor.  Brad: Oh my goodness. Those were good years, Dan!  Dan: For too many years. Brad: And now look, you’re like, famous. Dan: Famous? … cool because the work has gone so much more than just identifying genes to that toxin, but it’s opened up this whole … (SIO). You can find the podcast on Apple , Google , Spotify , Stitcher , directly with the RSS link , and via most …

… The publications resulting from such efforts should specify the collaborative nature of the project. Journal policies … users understand who contributed to the work, and to identify those who contributed significantly.    Authorship … products produced through all user projects accepted FY22 and later. …

… available from all the facilities participating in the FY25 call, introduces the available APS resources, and … The FY23 FICUS Open Call for Proposals describes the resources … available from all the facilities participating in the FY23 call, introduces the Eco-FAB resource, and contains …

… was at the Broad Institute in Cambridge, Mass. for a couple years before joining Warp Drive. And what kind of pushed me … time. And yeah, I mean, that was let’s see, maybe 5,6,7 years ago, and I’ve – I haven’t looked back. ALISON: So you … to be involved in signaling. We’re not perfect at identifying what these pathways are yet. So there’s still a lot to …

… we are today, recording today. BRIAN BACHMANN: Yeah, in the year 2000. And I was trying to figure out what to do with … out gene clusters maybe once a month at most. Maybe twice a year, a full gene cluster would come out. And it was a very … how much blood, sweat, and tears went into trying to identify that you had the right cluster before you sent it out for …

… The JGI is represented at conferences year round; find out where our researchers will be …

… of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary metabolism … that, I wanted to tell a quick story. Looking back, the year was probably 2010, 2011, I was a, uh- actually, I’ve … time. So they had actually sequenced the genome a number of years earlier as one of the first Streptomyces genomes that …

… program. And I’m a scientist here. And have been for 18 years. (LAUGHS) DAN UDWARY: All right. Easy start. What does … CSP call. That call is supposed to come out in early next year. Same for the FICUS, we’re working with EMSL and DOE … and that policy essentially states that we provide a one year embargo to sequencing data and metabolomics data. That …