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… enediynes – that’s a class of natural product with a really cool chemical structure. We try to explain it, but it’s … you as “the enediyne guy”. And so enediynes are this really cool class of natural product compounds, Alison. They are – …

… Program, which I was hired into, and my job is to do cool research, and also to talk to the wider natural … going on and what the context for their work is.  ALISON: Cool. That sounds great. I’m so glad that you invited me to … tell.  ALISON: It could be bacterial blankets, or coats, or water bottles, in a metaphor…. DAN: Or because they’re …

… on I worked with Bacillus for quite a while.  DAN: That’s cool that your dad inspired you because my kids have no … especially when I’m doing brewing. But that’s really cool.  NIGEL MOUNCEY: Yeah, dad never forced it on me, but … [LAUGHTER] We were just trying to keep our head above water and find cool things. So it was a very research …

… a few talks on that. Can you tell us why cone snails are so cool? ERIC:  So cone snails are basically shelled mollusks … this because one of the compounds that I thought was really cool – found in marine animals – was a peptide. And we had … making compounds.  DAN:  Alright, that sounds really cool.  ERIC:  It is really cool. So thanks to the JGI for …

… coast in the Adriatic Sea, and I thought, wouldn’t it be cool to look at these– it was actually marine invertebrates … It was the first year that they offered this. And the cool thing about it was that it had an international … And I love the smell of them. [LAUGHTER] I think they look cool. Yeah, I think I’ve made my point. They’re just all …

… in chemistry with a hobby of putting your head underwater. But thankfully that worked out. And I spent 30, 40 … time. Well, finally we convince people that we could get cool things. And so about the same time– this was around … Copious nutrients. DAN UDWARY: Never heard that word. OK, cool. BILL FENICAL: Copiatrophic organisms, which are minor …

… years through increased efficiency and diversification of clean energy sources.  The four Centers are located in …

… one began in late 2013, when a large patch of warm ocean water about a third the size of the United States began … Alaska. Over the next two years it slowly spread, raising water temperatures by a few degrees. Eventually The Blob … University of British Columbia was already collecting ocean water samples when The Blob started. The samples were taken …

… PCE (perchloroethylene) found its way into the groundwater of several communities in New Mexico via leakage from a local dry-cleaner. Researchers  identified two bacteria,  … rely heavily on groundwater as their only source of clean drinking water. Over 90% of the PCE in the groundwater has …

… the streams where the hills, as it rained or whatever, any water that washed down off the hills might carry small … term that really kind of fit and stuck. ALISON TAKEMURA: Cool. And so how did you get involved in genome mining? DAN … interesting biosynthetic pathway because fungal genes are cool. And if you like fungal genes, you should go back and …

… JGI is a key driver in some of the science. ALISON: Very cool. Yeah, and I see a lot of these secondary compounds on … weaken a cell wall, then the bacteria will just pop like a water balloon. But, you know, if you make modifications to …