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… together to try to understand the enzymology of their synthases so that we can start to use the DNA sequence to … many different directions. And if somebody brings some new approach or some new way of thinking or technology, that’s … this food web and this community that may be in some way selected by the cyanobacteria. And I think something very …

… The purpose of this policy is to establish communication norms around JGI contributions, ensure … recognized and credited for their work, while also adhering to the authorship policies of the journal in which the … that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to …

… DAN UDWARY: Hey everyone and welcome back to a new session of … chagrin found that they had the same conserved polyketide synthase and then P3. We still don’t know why 20 years … an interesting question. We’ve used a lot of different approaches. Some of them have been actinomycete-specific …

… “Adopt a Genome” is an informal program for faculty to … faculty will work with undergraduates in the analysis and publication of the claimed genome sequences. This … of classroom modules Currently 206 genomes have been selected with 11 published manuscripts published to-date …

… and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … of those kinds of genes. So we know what a polyketide synthase looks like. We know what a non-ribosomal peptide or … In a really more general population that isn’t selected for interesting chemistry, you’re going to find …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … just being out in the ocean, you can see these beautiful nudibranchs, these sea slugs, and finding out that there’s a … that’s making these compounds? So in the end, we took an approach that was kind of a simplified metagenome sequencing …

… And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … to look for right? And so, like, a type I polyketide synthase is very easy to search for because there are … sure. So I wanted to talk to you a little bit about your approach to that and what you guys do when you’re exploring …

… and keep it alive for a while. It does it because it’s been selected for. So if you think about the possible functions … about all that chemical diversity. So there are two ways of approaching it. One is there is a school of thought that … the raw material– for example, in the cases of polyketide synthases, the fatty acid synthases should actually be the …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … natural products and fungi are induced by growing beside a bacterium and I’m sure the opposite way around, because … thing is though, you might have the same backbone gene synthases, but having a different decoration enzyme actually …

… Every approved proposal starts with a User Agreement — before any … Non-Proprietary User Agreement and Appendix. An Appendix identifies the type of work or specific proposal to be … rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is …