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… of single-cell methods to access genetic material of uncultivated taxa of interest. One such effort is targeted at environmental cells that are from candidate phyla, major branches in the phylogenetic … in the strongly biased representation of sequenced genomes in the public domain, the bulk of which belong to …

… approaches to identify and characterize genomic information from uncultivated microbes and viruses. We develop computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial … on the assembly of metagenomic sequence data into microbial genomes, which is of fundamental value to improving our …

… focus on expanding molecular capabilities and functional genomics, scaling capacity through end-to-end automation — and further advancing sequence applications, single cell genomics, DNA synthesis, and metabolomics … profiling transcription factor binding sites across entire genomes. This technology has been further scaled to a …

… and evolutionary parameters driving virus:host dynamics in environmental microbial communities. This involves both experimental and computational exploration of uncultivated viral diversity, characterization of molecular … mechanisms involved in virus:host interaction and host cell take-over by viruses, and attempts to evaluate …

… that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to … is done in a timely fashion. The publications resulting from such efforts should specify the collaborative nature of … with a list of JGI staff who contributed to their project, using the CRediT taxonomy ( credit.niso.org/ , with …

… the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our group also … technology in order to enhance the quality of single-cell genomes and directly link functional information … internal analytical standards to accurately measure environmental microbiome activity levels.This functional …

… bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning to … discovering and characterizing giant viruses, which possess genomes and particle sizes that rival those of cellular …

… The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis … interactions. These insights are crucial for addressing key environmental challenges, such as improving soil health, … to generate high-quality genomic datasets, particularly for uncultivated microorganisms, by sequencing large populations …

… for faculty to “claim” the JGI’s unpublished microbial genomes, with the expectation that faculty will work with undergraduates in the analysis and publication of the claimed genome sequences. This … talent for biosciences.  Adopt-a-Genome has: ~20 faculty from institutions across the country Efforts in ongoing …

… DNA synthesis and pathway engineering Mass spectrometry based metabolomics Below is a table of standard product … the product and deliverables as well as target cycle times from sample receipt to completion of standard analysis.  Raw … and quality of finished product depend on genome. Selected genomes will be improved based on feasibility and scientific …

… Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … potential, with implications for energy production, environmental sustainability, and many other applications. … catalog of viral, microbial, and microeukaryote genomes and mobile genetic elements, linked to custom …

… provides customized analysis, the JGI also participates in publication of results. … FICUS call with EMSL begin with a Letter of Intent (LOI) from a researcher, briefly describing the project … The ranked proposal list, along with a recommendation from management at the JGI and the other participating …