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… The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … genetic elements. Beyond exploring and characterizing microbial diversity, work in the Metagenome Program uses … in natural environments. Integrating metatranscriptomes and metagenomes can, for instance, deepens our understanding of …

… computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial … applications. By recovering population genomes from metagenomes, we gain insights into microbial interactions, … high-throughput SIP (Nuccio et al. 2022) and terabase-scale metagenome combined assemblies (Hofmeyr et al. 2020) we are …

… for faculty to “claim” the JGI’s unpublished microbial genomes, with the expectation that faculty will work with undergraduates in the analysis and publication of the claimed genome sequences. This … talent for biosciences.  Adopt-a-Genome has: ~20 faculty from institutions across the country Efforts in ongoing …

… The JGI’s Microbial Program focuses on using cutting-edge sequencing, … provides high-quality, large-scale genomic data to advance microbial research that drives sustainable solutions in … The Microbial Program focuses on using advanced sequencing technologies to explore microbial diversity — with an emphasis on bacteria and …

… that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to produce manuscripts for publication and the responsibility for leading the efforts … is done in a timely fashion. The publications resulting from such efforts should specify the collaborative nature of …

… parameters driving virus:host dynamics in environmental microbial communities. This involves both experimental and … and virus genomes have been assembled and reported from metagenomes, our understanding of the impacts of these … invaluable information on virus diversity and activity in microbial communities, however they can only provide a …

… discovering and characterizing giant viruses, which possess genomes and particle sizes that rival those of cellular … Cataloging Earth's microbial lineages through advanced genomic techniques and … reveal new lineages and functional capabilities in the microbial world. …

… the product and deliverables as well as target cycle times from sample receipt to completion of standard analysis.  Raw … Constructs <5kb in size Single gene or multiple small genes assembled to less than 5kb in length, cloned into vector of … metabolites and unidentified features in spectra. 167/214 Metagenome Metatranscriptome Environmental transcript …

… Applications group explores the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our … technology in order to enhance the quality of single-cell genomes and directly link functional information with … DNA amplification, and sequence analysis to recover the genomes of uncultivated microbes. We also apply labeling …

… and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … and archaeal genomes that were created – these are Metagenome Associated Genomes, or MAGs. So these are genomes … set of MAGs to date. Here, at JGI, we took more than 10,000 metagenomes, many of which were sequenced at JGI, and some …

… profiling transcription factor binding sites across entire genomes. This technology has been further scaled to a … DNA amplification, and sequence analysis to recover the genomes of uncultivated microbes. We also apply labeling …