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… The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … and characterizing microbial diversity, work in the Metagenome Program uses several experimental approaches to … The Metagenome Program focuses on the high-throughput sequencing …

… approaches to identify and characterize genomic information from uncultivated microbes and viruses. We develop … computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial … applications. By recovering population genomes from metagenomes, we gain insights into microbial interactions, …

… for faculty to “claim” the JGI’s unpublished microbial genomes, with the expectation that faculty will work with undergraduates in the analysis and publication of the claimed genome sequences. This … talent for biosciences.  Adopt-a-Genome has: ~20 faculty from institutions across the country Efforts in ongoing …

… that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to produce manuscripts for publication and the responsibility for leading the efforts … is done in a timely fashion. The publications resulting from such efforts should specify the collaborative nature of …

… While an ever-increasing number of phage and virus genomes have been assembled and reported from metagenomes, our understanding of the impacts of these … the range of virus-host interactions occurring in microbiomes, these omics data must be complemented with …

… and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … and archaeal genomes that were created – these are Metagenome Associated Genomes, or MAGs. So these are genomes that were assembled from metagenomic sequence, metagenomic sequence …

… 2014), unearthing hundreds of thousands of new viral genomes and their predicted hosts (Nature 2016, Science … 2018, Molecular Cell 2019) and massive reconstruction of genomes from uncultivated microbes (Nature 2019). Other projects in … al. (2021) CheckV assesses the quality and completeness of metagenome-assembled viral genomes. Nature Biotechnol . …

… the product and deliverables as well as target cycle times from sample receipt to completion of standard analysis.  Raw … Constructs <5kb in size Single gene or multiple small genes assembled to less than 5kb in length, cloned into vector of … metabolites and unidentified features in spectra. 167/214 Metagenome Metatranscriptome Environmental transcript …

… discovering and characterizing giant viruses, which possess genomes and particle sizes that rival those of cellular … to adapt to live in Earth&#039;s most extreme environments, from deep-sea oceanic fluids to hypersaline lakes and … Leveraging artificial intelligence to extract insights from large-scale biological datasets: Our group develops and …

… catalog : Beyond minimal draft and improved draft microbial genomes the program offers single-cell sequencing, … Expansion of sequence space:  The JGI generates reference genomes from diverse bacterial and archaeal lineages to improve … capability of microbial communities based on their metagenome sequence, in the context of reference isolate …

… JGI serves more than 2,500 users that predominately come from the public sector: academic and government institutions … platform enables users to test hypotheses via designed and assembled physical DNA constructs that can then be … Our metabolomics platform delivers rich metabolite profiles from diverse biological and environmental samples by using …