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… behind phenotypic evolution. It also utilizes advanced tools, including deep learning algorithms for gene … folding models, to improve the accuracy of functional predictions and speed up genome analysis. Additionally, the … the ability to discover syntenic orthologs, generate publication quality graphics and explore pangenome views of …

The JGI has a strong interest in seeing that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to … (see Auspice Statement below) for the generation of sequence or metabolomic data, DNA synthesized, and any …

… that can trick an enzyme into thinking that that’s its substrate. And then when the enzyme tries to turn it over … that structural diversity it encodes for communication specificity. So it’s important to be able to tell what … up on previous Natural Prodcast episodes  here . Show Notes Publication: Suo Z et al. A Mesorhizobium japonicum quorum …

… support users, our efforts include developing computational tools for predicting biosynthetic gene clusters (BGCs), … BGCs that alleviate the constraints of cells and allow for substrates to be directed towards secondary metabolite … their binding sites across multiple genomes. Computational prediction of heterologous expressability: We are developing …

… faculty will work with undergraduates in the analysis and publication of the claimed genome sequences. This opportunity, provided … insights from sequence data, employing IMG data and tools for comparative analysis, visualization and …

… and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … We compare those sequences with our sequence. The premier tool for that these days, the one that pretty much everybody … form is not an easy task at all. So you can make all the predictions in the world that you want, but until you have …

The JGI’s Metabolomics Program works to uncover the roles of small molecules in biological systems, linking them with … of energy and nutrient exchange, as well as microbial and plant responses to environmental changes. With advanced mass spectrometry techniques and computational tools, the program supports foundational research related to …

Prodcast episode 17. The guest we have this week is Professor Cassandra Quave from Emory University, with joint … I think on COVID that we’re getting ready to submit for publication and have found some interesting hits for that as … get a DNA sequence first. And there are plenty of software tools to find natural product gene clusters, and even be …

DNA synthesis and pathway engineering Mass spectrometry based metabolomics Below is a table of standard product offerings, including a description of … contigs. Assembly, annotation ( IMG ) Depends on project Plant and Algal Standard Draft Whole genome shotgun …

… the same in the Venn diagram. DAN UDWARY: Do you need less specificity to be a broadly useful biocatalyst? Is that the … they’re making. And you want to have good binding to your substrate and high turnovers. But if you have those things, … work with in the lab. That’s something– ancestral protein prediction, reconstruction is a whole field. There’s a lot …