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… that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to … (see Auspice Statement below) for the generation of sequence or metabolomic data, DNA synthesized, and any … to navigate to the proposal info page. Use a URL Navigate directly to the proposal info page by using the URL …

Sample and library preparation, DNA synthesis and pathway engineering Mass spectrometry based metabolomics Below is a table of standard product offerings, including a description of … percentile*) DNA Synthesis Constructs <5kb in size Single gene or multiple small genes assembled to less than 5kb in …

Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … these hidden biochemical resources by exploring the genetic pathways responsible for their synthesis. The Secondary … the constraints of cells and allow for substrates to be directed towards secondary metabolite synthesis. We are …

… the only way a primary metabolite or a primary metabolic pathway is good for anything, it is if the final product is … one, and more often natural product biosynthesis is very directional. That’s wrong. DAN UDWARY: So how do you test … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

… … DAN UDWARY: Hey everyone and welcome back to a new session of Natural Prodcast. I’ve got two things I wanted to tell … mining company, back when DNA sequencing of natural product pathways was hard and expensive to do. As I said, Brian is … in graduate school, then Frances Arnold’s papers came out, directed evolution, and Pim Stemmer. And at the time, I …

… tools and how to really access and manipulate these pathways to get new compounds. And lots of– had some really … metabolism for a while now, a long time. But when our new director, Nigel, Nigel Mouncey ( who also has a podcast … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever …

… … Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … identify and interpret biosynthetic, secondary metabolism pathways. And today, we get to present our conversation with … we recently got awarded. And this is indeed one of the new directions that my group will be going into. And one of the …

… and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … cluster. And so we’ve learned a lot about how biosynthesis pathways happen, just by being able to find one kind of gene … we’re going to know enough about how things work in both directions in terms of how a biosynthetic cluster makes a …

… the field is many people come at it from many different directions. And if somebody brings some new approach or some … where you start to do oxidation. DAN: There’s another pathway? That’s the one I remember from grad school. … up on previous Natural Prodcast episodes  here . Show Notes Publication: Suo Z et al. A Mesorhizobium japonicum quorum …

… schedule. This should be coming out on the first Thursday of the month, just like I promised. Now I just have to make … sensing and its effects on regulation of natural product biosynthetic pathways, which led her to a successfully funded JGI CSP …

… faculty will work with undergraduates in the analysis and publication of the claimed genome sequences. This opportunity, provided … while nurturing a fresh cohort of users Reach the next generation of genome scientists and recruit new talent for …

… going to kick things off today with my interview with the Director of the Joint Genome Institute and head of the … me really interested in microbial gene regulation and some pathways. And I thought I’d take an academic job then, but I … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …