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… to ensure a robust offering of sequencing capabilities and products to our users. This includes scaling the … automation — and further advancing sequence applications, single cell genomics, biodesign, and metabolomics capabilities.    … profiling transcription factor binding sites across entire genomes. This technology has been further scaled to a …

… the product and deliverables as well as target cycle times from sample receipt to completion of standard analysis.  Raw data is provided for all sequencing products below. In addition, JGI will submit raw sequence … data is submitted to the  MassIVE repository . Not all products are available for all proposal calls.   Please …

… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa … such effort is targeted at environmental cells that are from candidate phyla, major branches in the phylogenetic … of which belong to only three phyla. The Woyke group uses single-cell sequencing as a means to begin filling this gap. …

… that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to produce manuscripts for publication and the responsibility for leading the efforts … is done in a timely fashion. The publications resulting from such efforts should specify the collaborative nature of …

… approaches to identify and characterize genomic information from uncultivated microbes and viruses. We develop … computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial … on the assembly of metagenomic sequence data into microbial genomes, which is of fundamental value to improving our …

… for faculty to “claim” the JGI’s unpublished microbial genomes, with the expectation that faculty will work with undergraduates in the analysis and publication of the claimed genome sequences. This … talent for biosciences.  Adopt-a-Genome has: ~20 faculty from institutions across the country Efforts in ongoing …

… Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … catalog of viral, microbial, and microeukaryote genomes and mobile genetic elements, linked to custom … in natural environments. Integrating metatranscriptomes and metagenomes can, for instance, deepens our understanding of …

… topic in, arguably, my area of expertise, which is genome mining. You’ll hear us talk about what it is, hear me make a … I got the chance to do genome mining on more than 50,000 genomes that we derived from meta-genome sequences. As … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, …

… mechanisms involved in virus:host interaction and host cell take-over by viruses, and attempts to evaluate … While an ever-increasing number of phage and virus genomes have been assembled and reported from metagenomes, our understanding of the impacts of these …

… technology in order to enhance the quality of single-cell genomes and directly link functional information with … The JGI provides users access to cutting-edge cell sorting, DNA amplification, and sequence analysis to recover the genomes of uncultivated microbes. We also apply labeling …

… We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning to … discovering and characterizing giant viruses, which possess genomes and particle sizes that rival those of cellular organisms. Giant viruses challenge the traditional …

… is always associated with toxicity, basically, killing cells. ALISON: Right, because they’re so reactive. BEN: … well. One is to do DNA sequencing. So upon sequencing many genomes, now we don’t have to, as in the past, go randomly … DAN: Yeah, I don’t think your lab is gonna tackle that single handedly, right? So, yeah, getting the community …