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… of secondary metabolism. Welcome back. This will be episode 12 of Natural Prodcast. And it’s our conversation with … Europe. So if there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And … this? NADINE ZIEMERT: It wasn’t that long ago, but maybe 2006, 2007, or something like that. And we actually found the …

… in this hypersaline environment, which can range from 8% to 28% salinity. We have toxic metals, so these concentrations … there a way to do that? DAN UDWARY: Well, so there’s good news and bad news on that. So one of the things that we’re … happening. And so we should have somewhere around 10, 11, 12 million BGCs in the database on the release, and that’s …

… as well as a unique opportunity to complete a California K-12 science or math teaching credential as an undergraduate …

Right, because they’re so reactive. BEN: …going back to the 1950s. But the structure of which was not known until the … right? BEN: Yeah, yeah. Well, we are at [10 to the] minus 12 [Molar concentration]- is sufficient to kill cells. So … So I wanted to ask you also about – because you were in the news recently – TSRI has acquired the Pfizer strain …

… internship partnership that started in the summer of 2014. … Modeled on the JGI-UC Merced internship program, a … within the realm of education. … Through the Berkeley Lab K-12 program, the JGI collaborates with Biotech Partners to …

… getting them out to you all. But for now, here is episode 10 of Natural Prodcast, the primer on genome mining. Hey, … in Yu et al, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 1253–1262, 70:3 ALISON TAKEMURA: And so did you succeed in … Microbiomes” paper is here . Read the associated JGI news release here . Software we discussed, used for genome …

… recruit new talent for biosciences.  Adopt-a-Genome has:  11 CSU educators working with the JGI 120 genomes claimed (or about one per student) Seven … et. al.  2023 . Microbiology Resource Announcements. 2023 12 (10), e00548-23 Whole genome sequence of the denitrifying …

… metagenomics. Nature Reviews Microbiology volume 20, 721–736 JC Villada, F Schulz (2022) The endosymbiotic box of … binning of a giant virus. mSystems. 5 (3) Schulz et al. (2018) Hidden diversity of soil giant viruses. Nature Communications. 9 (1), 1-9 Schulz et al. (2017) Towards a balanced view of the …

… like a nice summer day in Seattle I think this was like 2013 or 2014. And antiSMASH — I know you’ve interviewed Marnix … access to the whole sigma catalog of precursors in their 12C form. You can feed those and look for incorporation in … signal . mBio. 2023 Aug 31;14(4):e0101023. doi: 10.1128/mbio.01010-23. Publication: Cummings DA Jr. Methylotroph …

… people what that number is. BETSY PARKINSON: So micromolar, 10 to the negative 6th. Nanomolar, 10 to the negative 9th. Picomolar, 10 to the negative 12th. DAN: Yeah. So very-- BETSY PARKINSON: Very, very-- … the issues is in order to make the tetrapeptide, that's a 12 membered ring. And there's extreme ring strain in 12 …

… 109% 2,164 2,136 98.7% Q2 2025 175 152.100 87% 2,117 2,112 99.8% Q3 2025 175     2,140     Q4 2025 175     2,167     … 167.731 191% 2,140 2,184 102.1% Q4 2022 87.500 180.078 206% 2,164 2,208 102.0% *Includes Illumina and PacBio … 2020 71.000 71.189 100.% 2,140 1,824 85.2%† Q3 2020 71.000 28.127 40% 2,140 576 26.9%†† Q4 2020 71.000 123.993 175% …