Top image: From a single bacterial cell (seen here in a glass capillary), researchers sequenced and assembled the first complete genome of an uncultured symbiont (Candidatus Sulcia muelleri DMIN). (Woyke T et al. (2010) One Bacterial Cell, One Complete Genome. PLoS ONE 5(4): e10314. https://doi.org/10.1371/journal.pone.0010314)
Bottom image: The single cell was isolated from the bacteriome of the green sharpshooter Draeculacephala minerva bacteriome. (Damon Tighe)