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Microbial Program
… in particular to study inter-organismal interactions. Novel approaches are being explored to predict microbial … laboratory isolation and genome sequencing of underexplored bacterial and archaeal lineages that are important for … resequencing, RNA sequencing and epigenomics. Expansion of sequence space:  The JGI generates reference genomes from …
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Partnerships: Adopt-A-Genome
… in the analysis and publication of the claimed genome sequences. This opportunity, provided by the Department of … … A primary purpose of this project is to bring educators from a broad range of disciplines up-to-speed with some of … sequence to biological inference. … Genome sequences of key bacterial symbionts of entomopathogenic nematodes: …
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New Lineages of Life Group
… is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, …
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Metagenome Program
… regulation, and noncoding RNAs in microbiomes. The insights from this work have the potential to drive innovations in … most pressing challenges. … Exploration of phylogenomic novelty: Advances in metagenomic sequencing, assembly and … comprising the largest public collection of plasmid sequences identified from genomes, SAGs, MAGs, metagenomes …
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Natural Prodcast Episode 19: Bill Fenical
… learned a lot so much history from this conversation about why the ocean was basically unexplored until the 70s, and … an exploration into the secondary metabolism of some more novel marine bacteria. You know, I first met Bill as a … forward to seeing the data when it finally gets off the sequencers. The pandemic has obviously slowed JGI down a …
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Products
… the product and deliverables as well as target cycle times from sample receipt to completion of standard analysis.  Raw … sequencing products below. In addition, JGI will submit raw sequence data to  SRA at NCBI once the standard analysis is … physical separation of a biologically relevant unit from a microbial community, such as a microcolony, microbial …
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IMG Group
… fraction, AF) have been computed for nearly 28,000 bacterial and archaeal genomes. By clustering genomes based … species specificity of single cells and genomes extracted from metagenomes, and also as a metric for quality control … distribution of microbial genome and microbiome datasets sequenced at the JGI. IMG/M is also open to scientists …
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Natural Prodcast Episode 10: A Primer on Genome Mining
… more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene … machine learning really would help distinguish and predict novel gene clusters. DAN UDWARY: Yeah, it certainly could. …
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Natural Prodcast Episode 15: Katherine Duncan
Duncan: Yeah. I love actinomycetes. Dan Udwary: Tell us why. I mean, I know, but I think– Alison Takemura: I want to … of almost finished characterizing them. We’ve got genome sequences, which are just incredible. We’ve looked at the … currently exist. We looked at chemistry, so it’s really novel. And they’re just really exciting. And it really kind …
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Natural Prodcast Episode 21: Elizabeth Parkinson
… about several different pieces of her work, including bacterial quorum sensing and its effects on regulation of … The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain …
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Sequencing Submission Requirements for DNA Synthesis
When submitting sequences to the JGI DNA Synthesis program, please include the following items: … Sequence files for all constructs should be emailed to  … several easy-to-use open source tools for converting DNA sequence files into well-formed GenBank files. ApE is an …
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Natural Prodcast Episode 24: Jackie Winter and SMC
… is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a … seems to be a new structure, and the microorganisms are novel. I mean, we have Streptomyces , but they’re new …
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