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Microbiome Data Science Team
… data science.  Research in the Kyrpides group focuses on Microbiome Data Science and analysis of Big Data. The … al. (2017) Protein structure determination using metagenome sequence data. Science   355(6322):294-298 Paez-Espino D. et … al. (2015) Microbial species delineation using whole genome sequences. Nucleic Acids Res. 43(14):6761-71 Kyrpides NC et …
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Sequencing Submission Requirements for DNA Synthesis
When submitting sequences to the JGI DNA Synthesis program, please include the following items: … Sequence files for all constructs should be emailed to  … several easy-to-use open source tools for converting DNA sequence files into well-formed GenBank files. ApE is an …
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Metagenome Program
… of biogeochemically-relevant pathways, enabling modeling of microbiomes based on functional traits. These advancements … activity, transcription regulation, and noncoding RNAs in microbiomes. The insights from this work have the potential … comprising the largest public collection of plasmid sequences identified from genomes, SAGs, MAGs, metagenomes …
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Who We Are
… as the DOE Systems Biology Knowledgebase and the National Microbiome Data Collective.        … Learn more about our …
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Secondary Metabolites Program
… can unlock new avenues for bio-based products and bioenergy crop enhancement. The program aims to tap into the largely … computational analyses of BGC size and complexity, BGC sequence composition, metabolic similarity & compatibility, … of horizontal gene transfer. … The SMC provides complete sequence and annotation data for secondary metabolite …
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Sequencing Technologies
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Mission
… in doing so enabled the JGI to be the first to publish the sequence analysis of the target chromosomes 5, 16, and 19, … DOE science mission areas of bioenergy and environmental microbiome processes.  Among the JGI’s largest dedicated … nutrient cycles, those that impact sustainable bioenergy crop growth or global nutrient cycling, and and those …
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Natural Prodcast Episode 4: Nancy Keller
… out introns and dealing with, you know, weirdness in the sequence. You know, some clusters are not clustered…   … it so easily with fungi. So…   NANCY: Yeah, I don’t know why. For example, with that – actually there’s a good talk … the Peace Corps. And then from there, you know, how are our crops and people – in particular in developing countries – …
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Natural Prodcast Episode 10: A Primer on Genome Mining
… more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene … Nature Biotechnology, titled ‘A genomic catalog of Earth’s microbiomes’ . (Citation: Nayfach S et al. A Genomic Catalog …
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New Lineages of Life Group
… and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, … coding potential to find novel functions that may impact microbiome structure and biogeochemical cycles. Research … Towards a balanced view of the bacterial tree of life. Microbiome. 5 (1), 1-6 Schulz et al. (2017) Giant viruses …
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Partnerships: Adopt-A-Genome
… in the analysis and publication of the claimed genome sequences. This opportunity, provided by the Department of … builds upon thousands of microbial genomes that have been sequenced by the JGI though not formally analyzed or … public datasets.  … The Integrated Microbial Genomes & Microbiomes system ( IMG/M ) supports the annotation, …
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Special Initiatives & Programs
… capabilities and products . A minimum request of 1 Tb of sequence data is required to qualify for BERSS. For DNA … both for laboratory research and for improving feedstock crops: Center for Advanced Bioenergy and Bioproducts … and personnel resources for genomic research and sequence-based science.  Projects include de novo generation …
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