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Microbiome Data Science Team
… data science.  Research in the Kyrpides group focuses on Microbiome Data Science and analysis of Big Data. The … grand challenges in Biology, with a special focus on microbiome research.  These efforts include exploration of … al. (2017) Protein structure determination using metagenome sequence data. Science   355(6322):294-298 Paez-Espino D. et …
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Sequencing Technologies & Products
… through end-to-end automation — and further advancing sequence applications, single cell genomics, biodesign, and … [QA/QC]), large-scale liquid handling automation, and sequence analysis. … analytical standards to accurately measure environmental microbiome activity levels. Learn more about SIP …
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Who We Are
… as the DOE Systems Biology Knowledgebase and the National Microbiome Data Collective.    … in doing so enabled the JGI to be the first to publish the sequence analysis of the target chromosomes 5, 16, and 19, … DOE science mission areas of bioenergy and environmental microbiome processes.  Among the JGI’s largest dedicated …
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Sequencing Submission Requirements for DNA Synthesis
… When submitting sequences to the JGI DNA Synthesis program, please include … Sequence files for all constructs should be emailed to  … several easy-to-use open source tools for converting DNA sequence files into well-formed GenBank files. ApE is an …
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Metagenome Program
… of biogeochemically-relevant pathways, enabling modeling of microbiomes based on functional traits. These advancements … activity, transcription regulation, and noncoding RNAs in microbiomes. The insights from this work have the potential … drive innovations in energy, environmental sustainability, microbiome manipulation, and other fields, offering new …
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Secondary Metabolites Program
… can unlock new avenues for bio-based products and bioenergy crop enhancement. The program aims to tap into the largely … to improving the resilience and productivity of bioenergy crops. … computational analyses of BGC size and complexity, BGC sequence composition, metabolic similarity & compatibility, …
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Natural Prodcast Episode 4: Nancy Keller
… out introns and dealing with, you know, weirdness in the sequence. You know, some clusters are not clustered…   … it so easily with fungi. So…   NANCY: Yeah, I don’t know why. For example, with that – actually there’s a good talk … the Peace Corps. And then from there, you know, how are our crops and people – in particular in developing countries – …
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Natural Prodcast Episode 10: A Primer on Genome Mining
… more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene … Nature Biotechnology, titled ‘A genomic catalog of Earth’s microbiomes’ . (Citation: Nayfach S et al. A Genomic Catalog …
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Partnerships: Adopt-A-Genome
… in the analysis and publication of the claimed genome sequences. This opportunity, provided by the Joint Genome … builds upon thousands of microbial genomes that have been sequenced by the JGI though not formally analyzed or … necessary to extract meaningful biological insights from sequence data, employing IMG data and tools for comparative …
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New Lineages of Life Group
… and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, … coding potential to find novel functions that may impact microbiome structure and biogeochemical cycles. Research … tool for generating synthetic sequencing data from genomic sequences …
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Special Initiatives & Programs
… capabilities and products . A minimum request of 1 Tb of sequence data is required to qualify for BERSS. For DNA … both for laboratory research and for improving feedstock crops: Center for Advanced Bioenergy and Bioproducts … National Laboratory: This center concentrates on “model” crops of rice and Arabidopsis, in the search for …
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Natural Prodcast Episode 6: Marc Chevrette
… at genomes and seeing where the really hard things to sequence were, and wondering what those … what those were … functional was these secondary metabolite pathways. So why was that? What is it about secondary metabolite pathways … getting really excited about January, we’re having our new crop of partner instructors come into Wisconsin so we can …
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