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… is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and viruses in … data. We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning to identify new divergent lineages and expand the Tree of Life. We then investigate …

… now I’m working on this the afternoon of the day I’m due to release it, which is not ideal for me keeping myself on … expression hosts like maybe in many fields now like in cyanobacteria or even [ Streptomyces ] coelicolor you’ll see … cluster with me because it turns out that oftentimes in bacterial genomes if you have a quorum sensing system or the …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … secondary metabolite peptides. And there are two ways that nature does this. The more well-known secondary metabolism … to chemistry. But there are also many other stories, waiting for good scientists to uncover. DAN:  So you’ve also …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … ALISON: Hmm. It kind of – it’s kind of like I’m smelling bacterial perfume. I mean – but it’s purposeful so it’s some … how funny, you know, the human endeavor of understanding nature is: we want to categorize things into these arbitrary …

… … DAN: All right. Welcome back to Natural Prodcast. I did it. I’m keeping to my schedule. … about several different pieces of her work, including bacterial quorum sensing and its effects on regulation of … DAN: Oh, I did not know that. That's cool. JACKIE: But nature can do this. BETSY PARKINSON: But nature can do it …

… in natural products right. There’s many different avenues toward chemistry. But that’s kind of where I had you. How … organs that solely house– whose sole function is to house bacterial associates. And so the one that the Hawaiian … an agar plate with a strip of the bacteria down the middle waiting two weeks sometimes for it to grow and then putting …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … through the stories I told you about geosmin, which is a bacterial sacred metabolite, and ergot alkaloids come from … But um, yeah, so secondary metabolism is throughout nature, except maybe for animals and humans, not as much. …

… … DAN UDWARY: Hey everyone and welcome back to a new session of Natural Prodcast. I’ve got two things I … in the marine ecosystems and marine actinomycetes and cyanobacteria. And we thought we could also– let’s see what … all sorts of different colors. I mean, where else in nature– and they’re not fungal. Where else nature can you go …

… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural … know a lot about them by their mate, what their role in nature, how have they been selected for or how do they … later. And she happened to work with nature products from cyanobacteria. So that’s how I started. I love the lab, I …

Hey, everyone. I’ve got a great episode for you here today. We got the opportunity to talk to one of the real legends of natural products, Professor …

DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural … doi: 10.1038/s41587-020-0718-6) The GEM catalog expands the bacterial and archaeal orders as seen on the phylogenetic tree, with new lineages of uncultivated genomes from the GEM catalog (in …

… and Sciences. She’s an ethnobotanist and the herbarium curator there, with a broad range of experimental work on plants … a check-up on me. And I wonder how that intersects with bacterial bioprospecting that is often done, where we’re … really interesting small molecules in nature that are just waiting to be found. They’re hard to get at. You have to …